Rare variants of adenocarcinoma of the prostate: a 25-year analysis of incidence and mortality

The vast majority of prostate cancers are adenocarcinomas of the prostate, i.e., cancers that start in the epithelial cells of the prostate gland. Most of these adenocarcinomas have a well-defined, “normal” cancer histology. However, there are five categories of rare adenocarcinoma, with differing levels of risk. … READ MORE …

Do SPOP mutations define a new molecular subtype of prostate cancer?

A Letter to the Editor just published in the journal Nature Genetics has suggested that that so-called SPOP mutations may be responsible for between 6 and 15 percent of the prostate cancers diagnosed in the USA each year. … READ MORE …

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