Active surveillance or immediate surgery for low-risk prostate cancer: let’s look at the math

A new study has attempted to calculate the impact of age, health status, and patient preference on the relative outcomes (and merits) of immediate surgery as compared to active surveillance for the management of low-risk prostate cancer.

RALP not associated with better continence, sexual function after prostate cancer surgery

The “New” Prostate Cancer InfoLink has long been pointing out the lack of any evidence that men who are treated with robot-assisted laparoscopic prostatectomy (RALP) will have better outcomes with respect to continence and sexual function than men who elect to have the older, ”open” form of radical prostatectomy.

The value of MRI prior to surgery as a treatment for localized prostate cancer

A recent media release from the Radiological Society of North America (RSNA) is headed, “Preoperative MRU may reduce risk of nerve damage in prostate cancer surgeries” … and this is absolutely true.

Patient satisfaction after first-line treatment for localized prostate cancer (in Germany)

A new article in the journal Anticancer Research suggests that patients had greater satisfaction after modern forms of external beam radiation therapy (EBRT) than after some other standard forms of first-line treatment. Of course the absolute truth of this conclusion may be affected by the details of the study.

Nerve-sparing surgery and post-surgical sexual function: news from Kyoto

According to a report from Prof. Thomas Aherling on the UroToday web site, there were three interesting presentations related to nerve-sparing surgery at the recent World Conference of Endourology and SWL, in Kyoto Japan.

Hazard for prostate cancer-specific mortality after radical prostatectomy

A new analysis of information from the Surveillance, Epidemiology and End Results (SEER) database suggests that the “hazard” for prostate cancer-specific mortality after radical prostatectomy is very low but that it does increase in a continuous manner for at least 15 years post-treatment.

Survey suggests high level of long-term side effects after treatment for prostate cancer

According to new data presented at the Frontiers in Cancer Prevention Research meeting ongoing this week in Boston, MA, some 70 percent of prostate cancer patients participating in a survey in Michigan reported long-term, treatment-related, adverse effects after first-line treatment with surgery or radiation therapy.

Is surgery appropriate for men with high-risk prostate cancer?

An article by Schmitges et al., originally published in Therapeutic Advances in Urology in August this year, has just been reproduced on the Medscape Oncology web site, where it is available in complete form.

Intraoperative, tumor-specific fluorescence imaging — will it work in prostate cancer?

A report just published on line in Nature Medicine describes the first use of intraoperative, tumor-specific fluorescence imaging to highlight the precise position of small groups of cancer cells in women with ovarian cancer, thereby allowing the surgeon to carefully excise such small groups of cells.

A new way to look at side effects of first-line prostate cancer treatment

Academic research into the side effects of different treatments for localized prostate cancer have long been hampered by the lack of consistently used criteria for the assessment of those side effects at baseline and at defined time-periods post-treatment.

Incidence of climacturia “surprising” to one leading surgeon

It is sometimes amazing how little some physicians appear to understand about the side effects of the treatments that they give to their patients! If these were really rare side effects it might be understandable, but the one we shall discuss below is far from rare …

Utilization of standard treatments for localized prostate cancer by Medicare beneficiaries

In a new paper just published on-line in the Journal of Urology, Kapoor et al. have provided data on trends in the utilization of various major types of treatment for the management of localized prostate cancer among Medicare beneficiaries in the USA between 2006 and 2008.

VED + taldalafil helps with return of erectile function post-surgery vs. taldalafil alone

A very small (pilot scale), randomized, clinical trial has provided some evidence that combining the use of a vacuum erection device (VED) with taldalafil (Cialis) drug therapy after bilateral, nerve-sparing robot-assisted laparoscopic prostatectomy (BNS-RALP) can improve the probability of return of erectile function post-surgery.

Patients’ decisions, patients’ expectations, and surgery for localized prostate cancer

Two articles and an associated editorial, currently in press in the Journal of Urology, offer insight into the pre-treatment expectations and the post-treatment realities of men who decide to have surgical treatment for localized prostate cancer.

Outcomes after surgery for spinal cord compression among men with metastatic prostate cancer

Spinal cord compression is a relatively common consequence of advanced, metastatic prostate cancer. Treatment has historically involved reconstructive surgery to relieve the compression and stabilize the spine.

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