BRCA1/2, prostate cancer, and the Angelina Jolie effect

According to an article in The Sunday Times in the UK over the weekend, a well-known surgeon in the UK is claiming to have carried out “the first” radical prostatectomy on a man with no other indicator for treatment except a BRCA2 mutation and a significant family history of breast and prostate cancer. … READ MORE …

Patient satisfaction during and after the decision to undergo radical prostatectomy for localized prostate cancer

A paper to be presented at the upcoming AUA annual meeting from what appears to be an ex-US group of clinicians continues to demonstrate the fact that many men get surgical treatment for prostate cancer without anything like a full appreciation of the clinical problem, their treatment options, or the potential consequences. … READ MORE …

Are the purported “safety issues” with the da Vinci robot real?

A long article by Lindsey Tanner of the Associated Press was published yesterday on the NBC News “Vitals” web site. It addresses the FDA investigation of reports of “problems, including several deaths” associated with the use of the da Vinci robot surgical system that we have previously referred to. … READ MORE …

It’s not the robot, it’s (almost certainly) the humans that are the problem

Prostate Cancer International, on this site and even more so on its associated social network, has long emphasized the importance of physician focus, skill, and experience as being key factors in the diagnosis and management of prostate cancer — regardless of the specific types of technology that may be being applied. … READ MORE …

Taller men seem to have greater risk for prostate cancer recurrence post-surgery

According to a poster recently presented at a South-Eastern Section meeting of the American Urology Association, there is a significant and independent relationship between male height and risk for biochemical recurrence after radical surgery as a treatment for prostate cancer. … READ MORE …

TRT after radical prostatectomy for localized prostate cancer in hypogonadal males

A new paper just published in the Journal of Urology addresses (again) the controversial issue of whether the use of testosterone replacement therapy (TRT) is appropriate as a management strategy after first-line treatment for hypogonadal patients. … READ MORE …

A 17 percent potency rate post-surgery in one Swedish study

According to another media release issued on Sunday by the European Association of Urology, only 17 percent of a large cohort of Swedish men with prostate cancer who were potent prior to surgery were still potent 18 months post-surgery (whether they had nerve-sparing or non-nerve-sparing surgery). … READ MORE …

Badly judged and biased political spin from the European Association for Urology

According to a media release issued by the European Association of Urology on Saturday, just prior to the opening of their annual meeting in Milan, Italy, “Surgery is superior to radiotherapy in men with localized [prostate cancer].” This headline is not even justifiable based on the content of the media release. … READ MORE …

Finally … Some long-term functional outcomes data on first-line treatment

An article in this week’s New England Journal of Medicine offers us 15-year functional outcomes data from the Prostate Cancer Outcomes Study (PCOS), which enrolled 3,533 men in whom prostate cancer was diagnosed in 1994 or 1995. … READ MORE …

Men in minorities or treated under Medicaid receive lower quality care

In yet another utterly unsurprising “research” finding, a new article in the Journal of Urology has shown that — in the USA — minority prostate cancer patients and prostate cancer patients treated under Medicaid are less likely to have their prostates removed at high-experience and high-volume hospitals where there is high use of robot-assisted surgical techniques. … READ MORE …

Shortened penile length after radical prostatectomy: what’s new?

The fact that there is a significant degree of risk for a reduction in penile length after radical prostatectomy for the treatment of localized prostate cancer is very definitely not news (despite the fact that all too few surgeons advise their patients of such a risk). However, an accurate assessment of the probability of this risk has never been well established. … READ MORE …

A real decrease in the use of RP in treatment of men with low-risk prostate cancer?

A new paper from clinical research teams at two French hospitals suggests that there has been a significant relative increase (from 2005 to 2010, at their institutions) in the percentage of men found to have pathological T3 as opposed to pathological T2 disease after radical prostatectomy (RP). … READ MORE …

More on age and urinary continence post-radical prostatectomy

We commented on Friday last week on a paper by Wallerstedt et al. addressing factors affecting risk for urinary continence after radical prostatectomy. One reader had asked us whether we could provide more details about the age breakdown and the rates of urinary incontinence in the patients studied by the Swedish research team. … READ MORE …

Sexual desire and sexual “bother” before and after radical prostatectomy

Experienced prostate cancer patients and advocates are well aware that patients’ attitudes to the importance of their sex lives are a critical factor in the decision process when treatment for localized prostate cancer has to be seriously considered. … READ MORE …

Speciality bias still affecting treatment recommendations for low-risk prostate cancer?

A majority of urologists and radiation oncologists are still not recommending active monitoring (“active surveillance”) as a first-line method for the management of patients with low-risk prostate cancer. … READ MORE …

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