Prostate Cancer International is
for 2011 by Great NonProfits
According to a media release issued earlier today, Medivation and Astellas Pharma have enrolled the first patient into a new Phase III clinical trial of MDV3100.
Filed under: Drugs in development | Tagged: castration-resistant, mCRPC, MDV3100, Phase III, trial | Leave a Comment »
According to a media release from a division of Johnson & Johnson earlier today, an independent data monitoring committee has recommended that patients in the placebo arm of a Phase III trial of abiraterone acetate be offered treatment with abiraterone following unblinding of study data.
Filed under: Drugs in development | Tagged: abiraterone, early access, trial | 8 Comments »
Many patients have sought out acupuncture as a method to gain relief from hot flashes associated with androgen deprivation therapy (ADT). However, data from prospective clinical trials is at best limited.
Filed under: Living with Prostate Cancer, Management | Tagged: acupuncture, ADT, androgen deprivation, hot flashes, trial | 3 Comments »
We note that the second Phase III clinical trial of abiraterone acetate — in asymptomatic or mildly symptomatic patients with metastatic, castration-resistant prostate cancer (mCRPC) who have not had either chemotherapy or ketoconazole therapy — is now fully enrolled (as of last Friday).
Filed under: Drugs in development, Uncategorized | Tagged: abiraterone, trial | 2 Comments »
We have heard that another investigational vaccine therapy has started Phase I clinical trials that will include patients with advanced prostate cancer who “have failed at least 1 course of an accepted hormonal therapy.”
Filed under: Drugs in development, Management, Treatment | Tagged: DPX-0907, trial, vaccine | Leave a Comment »
The pharmaceutical company Roche announced this morning that the combination of bevacizumab (Avastin) with docetaxel and prednisone does not extend the overall survival of men with hormone-refractory prostate cancer (HRPC) compared to docetaxel + prednisone alone.
Filed under: Drugs in development, Management, Treatment | Tagged: Avastin, bevacizumab, castration-resistant prostate cancer, CRPC, HRPC, survival, trial | Leave a Comment »
According to an e-mail from our friends at Us TOO the AFFIRM trial (A study evaluating the eFFicacy and safety of Investigational dRug MDV3100 in men with advanced prostate cancer) has started to enroll patients in the USA. It had started to enroll patients in Europe earlier this month.
Filed under: Drugs in development | Tagged: AFFIRM, MDV3100, Phase III, trial | 5 Comments »
A newly published Italian study offers what we believe to be the first direct comparison of two “modern” types of external beam radiation therapy for the treatment of localized, high-risk prostate cancer. This is a relatively small trial, with relatively brief follow-up to date, but the results are nontheless interesting and important.
Filed under: Management, Treatment | Tagged: "high risk", external beam radiation, localized, randomized, trial | 2 Comments »
Earlier this year we reported the initial results of a truly randomized Canadian trial of cryotherapy vs. external beam radiation therapy (EBRT) for the treatment of localized prostate cancer. The same group of authors have now reported follow-up data on quality of life.
Filed under: Management, Treatment | Tagged: cryoablation, cryotherapy, EBRT, external beam radiation therapy, randomized, trial | 2 Comments »
A new Phase III clinical trial is investigating the safety and efficacy of high intensity focused ultrasound (HIFU) for the treatment of locally recurrent prostate cancer following failed external beam radiation therapy (EBRT).
Filed under: Management, Treatment | Tagged: HIFU, trial | 2 Comments »
Bill-Axelson et al. have just published an update of the Scandinavian Prostate Cancer Research Group’s prospective, randomized trial of watchful waiting vs. radical prostatectomy. The most recent results are somewhat worrisome. For a detailed update on this study, please read the article entitled “Watchful waiting vs. radical surgery: the Scandinavian trial” elsewhere on this site. However, [...]
Filed under: Management, Treatment | Tagged: cancer, news, prostate, prostatectomy, radical, randomized, Scandinavian, trial, waiting, watchful | 3 Comments »
Search for new and
ongoing trials on the
CTAG PCa web site