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Many readers may be interested in an article on active surveillance and other forms of expectant management by Khurana and Stephenson that appears on the front page of the November issue of the AUA News. This article is based on a poster presented by Khurana et al. at the annual meeting of the American Urological [...]
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: active surveillance, expectant management, observation, watchful waiting | 1 Comment »
According to another publication based on data from the Physicians’ Health Study, “Quality of life outcomes in men who underwent delayed treatment after initially waiting were not worse than in men who underwent immediate treatment.”
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: immediate treatment, outcome, Physicians' Health Study, quality of life, watchful waiting | 7 Comments »
According to a report presented today at the annual meeting of the American Society for Radiation Oncology (ASTRO) in Miami Beach, Florida, men with localized prostate cancer who were treated 15 years ago with external beam radiation therapy had no significant survival benefit compared to men followed with watchful waiting.
Filed under: Management, Treatment | Tagged: comparison, outcome, radiation therapy, watchful waiting | Leave a Comment »
A new study in the Journal of Urology reports data on a cohort of 125 patients enrolled in the Physicians’ Health Study (PHS) who elected to be managed with watchful waiting for a minimum of 1 year after their initial diagnosis and who were followed for an average (mean) of 7.3 years.
Filed under: Management, Treatment | Tagged: active surveillance, long-term, outcome, quality of life, watchful waiting | 8 Comments »
In 1989 the Scandinavian Prostate Cancer Group Study Number 4 (SPCG-4) started randomizing men with a clinically initiated diagnosis of localized prostate cancer to either watchful waiting or open radical prostatectomy as their primary treatment. A new paper has now addressed the long-term quality of life (QoL) of men in this study.
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: adverse effects, outcome, quality of life, radical prostatectomy, Scandinavian, SPCG-4, trial, watchful waiting | Leave a Comment »
A new report in European Urology may offer some insights into the value of large, retrospective data analyses as compared to multi-center, randomized clinical trials when it comes to the assessment of the effects of different first-line treatments on the management of clinically localized prostate cancer.
Filed under: Management, Treatment, Uncategorized | Tagged: age, mortality, observation, radical prostatectomy, watchful waiting | 5 Comments »
On December 5 to 7 this year, the National Institutes of Health (NIH) is to hold an NIH State-of-the-Science Conference on the role of active surveillance and watchful waiting in the management of men with supposedly localized prostate cancer. It is free and open to the public or it can be monitored by web cast.
Filed under: Diagnosis, Management, Risk | Tagged: active surveillance, watchful waiting | Leave a Comment »
Bill-Axelson et al. have reported a second update to the results of the Scandinavian trial of radical prostatectomy (RP) compared to watchful waiting in patients with “early” (but not necessarily localized) prostate cancer
Filed under: Management, Treatment | Tagged: outcome, radical prostatectomy, watchful waiting | 6 Comments »
A new study reports on retrospective analysis of data from a series of 218 patients diagnosed between 1991 and 2005 with localized prostate cancer and who were managed using a “watchful waiting” (as opposed to an active surveillance) strategy at the Massachusetts General Hospital (MGH).
Filed under: Diagnosis, Living with Prostate Cancer, Management | Tagged: localized, outcome, risk, watchful waiting | 4 Comments »
New data from the Swedish national prostate cancer registry suggest that the 10-year prostate cancer-specific mortality rate is now less than 2.5 percent for men who opt for careful disease monitoring as opposed to immediate invasive treatment.
Filed under: Diagnosis, Management, Treatment | Tagged: active surveillance, localized, low risk, radiation therapy, radical prostatectomy, watchful waiting | Leave a Comment »
Many readers might be interesting in listening to (or reading the transcript of) a discussion between Ira Flatow of National Public Radio and Dr. Martin Sanda of Harvard University that was broadcast on the program “Science Friday” on September 4th.
Filed under: Diagnosis, Management, Risk, Uncategorized | Tagged: active surveillance, Diagnosis, expectant management, risk, watchful waiting | Leave a Comment »
An article by Linda Beck in the Health Matters section of the Wall Street Journal today weighs in on the pros and cons of “watchful waiting” as a management strategy that is increasingly considered appropriate for many men with low risk, early stage prostate cancer.
Filed under: Management | Tagged: active surveillance, expectant management, watchful waiting | 8 Comments »
McDermott and Sanda have just published an assessment of the recent re-analysis of the Scandinavian Prostate Cancer Group Study Number 4 (SPCG-4). This is the study that initially demonstrated a modest but significant survival benefit of prostatectomy over watchful waiting. According to the re-analysis of this study, patients allocated to watchful waiting experienced a significantly [...]
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: hormone therapy, quality of life, radical prostatectomy, Scandinavian trial, watchful waiting | 4 Comments »
It doesn’t tell us a great deal, but we are pleased to note the earliest publication of data from the Prostate cancer Intervention Versus Observation Trial (PIVOT), a multicenter, randomized, controlled clinical trial initiated in 1994 to compare the effects of watchful waiting to radical prostatectomy in men with localized prostate cancer.
Filed under: Management, Treatment | Tagged: PIVOT, surgery, watchful waiting | 6 Comments »
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