More weekend news reports: April 19, 2009

The reports discussed below deal with:

  • Positron emission tomography in prostate cancer management
  • HIFU and cryotherapy in focal therapy for prostate cancer
  • Does a prior TURP affect outcomes to radical prostatectomy?

Picchio et al. report that positron emission tomography (PET) and PET-computed tomography (PET-CT) can be successfully used in treatment planning in prostate cancer patients, at different steps along the course of the disease. However, they note that the potential role of PET and PET-CT in monitoring prostate cancer progression and the effects of treatment are under investigation and are still to be defined. A recent, prospective US study of the potential of PET in diagnosis and management of many cancers showed that the results of PET scans did not, at this time, significantly alter the decisions which experienced clinicians made about how to treat their patients, as compared to other available data. As a consequence, Medicare does not currently cover the use of PET scanning in the diagnosis or management of prostate cancer in the USA.

Li et al. have shown that, in a series of 127 consecutive Chinese patients, treated with either high-intensity focused ultrasound (HIFU) or targeted cryoablation of the prostate (TCAP), the tissue trauma and associated invasiveness of HIFU is significantly less than that of TCAP. Prior experimental studies have suggested that  acute-phase reactions to treatment are proportional to surgery-induced tissue damage.

Palisaar et al. have published data indicating that, in a modern patient series treated between 2003 and 2007, patients who had previously received a transurethral resection of the prostate (TURP) responded to radical retropubic prostatectomy (RRP) just as well as men who had had no prior TURP.

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