“Natural 33-ingredient compound” active against prostate cancer cell lines in vitro

Researchers at Columbia University are reporting that a complex mixture of 33 different nutrients, medicinal mushrooms, minerals, and herbs seems to have significant activity affecting the growth and survival of androgen-dependent and androgen-independent prostate cancer cells lines derived from mice and humans.

In their article just published in Integrative Cancer Therapies, Yan and Katz report that ProstaCaid — a product developed by Isaac Eliaz, MD — shows significant activity in the laboratory which could be indicative of a possible clinical effect in humans. However, we are not aware of any data suggesting that ProstaCaid is actually clinically effective as an agent that can prevent or be used effectively to treat prostate cancer at any stage of the disease.

We have noted many times before that drugs and drug combinations that can do wonderful things in laboratory tests and even in laboratory animals frequently have absolutely no clinical impact at all when tested in man compared to a placebo. This is not to say that ProstCaid “doesn’t work,” but this type of laboratory data should be considered as no more than one step on the road to the development of an agent that can be established as effective and safe in the prevention or treatment of a specific disease. Until such data are available, “you are on your own out there” with regard to the actual clinical value of this nutritional supplement.

In the same issue of Integrative Cancer Therapies, Yan and Katz have also reported on similar studies with two formulations of modified citrus pectin — PectaSol and PectaSol-C (also developed by Dr. Elias). Again, these data only show activity in the laboratory, not a clinical effect in man.

Before you decide to spend more than $150.00 for a “trial size” order of ProstaCaid or about $30.00 for a month’s supply of PectaSol-C, you might want to see some data that actually demonstrates a clinical effect in man. Caveat emptor!

5 Responses

  1. I agree that lack of clinical trials and research is a real problem with many integrative medicine approaches to advanced prostate cancer treatment, i.e. diet, supplements, etc. Unfortunately, those clinical trials will probably never occur because the pharmaceutical companies see no financial incentives to sponsor this kind of research.

    Let’s talk about conventional treatment for end stage advanced prostate cancer …. plenty of research and clinical trials that demonstrate that these enormously expensive drugs often have very limited value, empty your bank account, and often rob patients of quality of life in the final months of their lives. In the words of one of my physician friends who recently died from cancer, chemotherapy may the cruelest hoax in medicine.

    Yes, be careful about taking supplements, altering your diet, keep your physician informed of your approach. Be critical of the profit motive when considering alternative approaches to treatment. But , also be critical of all conventional approaches as well and for all the same reasons.

  2. Which comment is an excellent introduction to an article entitled “Letting Go” which is mentioned in the very next post.

  3. I believe that you missed my point. Of course, we all need to know when to “let go.”

    The point I was trying to make is that some of the integrative medicine approaches involving supplements and diet, even though untested in clinical trials with human subjects, may actually be a more appropriate choice for those of us with advanced prostate cancer. There are no known side effects in Dr. Eliaz’s supplements. The cost is a fraction of the cost of chemotherapy, with it’s well researched and limited usefulness.

    Hopefully, someday there may be a chemotherapy agent that will completely stop the progression of this disease without destroying quality of life. Until then, I will look elsewhere.


  4. I am 86 years old. I had 39 days radiation for one speck of cancer in 8 samples taken from my prostate at biopsy in August 2001, when I was 74. (My PSA had doubled from 2 to 4 in one year between 2000 and 2001.) By 2013 my PSA had gone up to 4.25 ng/ml in stages, but had doubled in 1 year from 2.0. Health Sciences Institute information led me to Dr. Isaac Eliaz, MD and his Pectasol C and Prostacaid. I took them for 4 weeks and my PSA dropped to 1.28. My UCLA Medical Center Oncologist noted the two-thirds reduction in PSA level and gave me a prescription for bicalutamide (50 mg/day). I will continue to work with my urologist and a local oncologist for prostate cancer said to be still contained in my radiated Prostate. Bone scan to be done.

  5. William Greene:

    This was in 2013. How are things? My husband was diagnosed with the same cancer, had his prostate removed, and now the PSA is doubling. Should I invest in this?

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