Smoking isn’t good for men with prostate cancer (redux)

Back in 2011 we commented on a report indicating that men who continued smoking after initial treatment for prostate cancer (or who were smokers up to 10 years prior to their treatment) were at significantly higher risk for prostate cancer progression than non-smokers.

These data have now been confirmed by newer data presented as the ongoing annual meeting of the European Association of Urology (EAU). A report on the data presented by Reiken et al. at the EAU can be found on the HealthDay web site. The new data appear to correlate extremely closely with the data first presented some 4 years ago now.

3 Responses

  1. There are always exceptions. My younger brother is a heavy smoker but has been free of prostate cancer for 14 years now. I have never smoked in my life yet I have recurrence after just 4 years, post-surgery and radiation. The variables in “The Beast” are legion, are they not?

  2. But of course. … The is no such thing as an “average” individual! But your brother is still not doing himself any favors … prostate cancer or not!


    I’m convinced that smoking is unwise. However, I’m still trying to figure out if smoking is a causal contributor to recurrence in prostate cancer or just a proxy representing a cluster of other unhealthy behaviors that contribute to an increased risk of recurrence.

    I just did a PubMed search for “tobacco AND prostate cancer”, getting 87 hits (from 444) after narrowing the results with these filters: Abstract, published in the last 5 years, Humans. Most papers do not have smoking or tobacco in the title, and most do not get into the mechanisms of action, based on scanning the titles. However, a paper from October 2014 addresses substantial changes among immune and inflammation markers for cigarette smokers. Any insights?

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