Modified poliovirus in treatment of metastatic prostate cancer?


Earlier this year (on March 29 to be precise) some of our readers may remember seeing a two-part 60 Minutes program about the use of a modified form of poliovirus in the successful treatment of some patients with deadly forms of brain cancer.

Now comes a news article on the web site of the Duke Translational Medicine Institute about initial steps to use the same technology in the treatment of men with metastatic prostate cancer.

This project is obviously in the very earliest stages, with preliminary tests in laboratory mice before anyone would consider trying this in patients. However, it is worth remembering that Nancy Justice, the first woman to be treated with the modified poliovirus for her brain cancer, appears to have gone into at least a very long-term remission.

If you want to go back and look at the original 60 Minutes program, the two parts can be seen here (for Part I) and here (for Part II). You might also want to have a look at the cautions about the use of this type of therapy in prostate cancer that we published on March 30 this year.

3 Responses

  1. It no doubt may be a while before this hits the clinic and there no doubt may be risks and implementation issues but it’s great to see some innovation.

    Between this and the copper study, I am happy to be a Duke patient. I hope I stay ahead of the beast long enough to see these options become a reality!

  2. I remember that piece on 60 Minutes.

    Not sure if it’s just me, but that first link didn’t work.

  3. Hi Jerry.

    Not sure what the problem was, but the link is working now.

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