Prostate ablation using HIFU — the role of patient preference information

A newly published review by staff of the Center for Devices and Radiological Health (CDRH at the U.S. Food & Drug Administration (FD) addresses the potential role for patient preference information (PPI) in determining patient perceptions of the “value” of high-intensity focused ultrasound (HIFU) and similar techniques in the management of prostate cancer.

5-year follow-up after focal therapy with HIFU for localized prostate cancer

A new paper from the Emberton-Ahmed group in the UK has reported 5-year follow-up data from a cohort of > 600 patients with clinically significant, localized prostate cancer, all treated with focal forms of high-intensity focused ultrasound (HIFU).

Targeted HIFU in the treatment of index lesions in localized prostate cancer

A new review article offers us some greater clarity related to the role of targeted, high-intensity focused ultrasound (HIFU) to treat carefully selected areas of the prostate to eliminate primary or index lesions while leaving the remainder of the prostate intact.

Patient choice and the effectiveness and safety of HIFU

An interesting article has just been published in the Journal of Urology which helps to provide information (and context) about the quality of data supporting the use of high-intensity focused ultrasound (HIFU) in the treatment of prostate cancer.

Major US insurer to cover use of HIFU for treatment of radiorecurrent prostate cancer

According to a media release issued on March 18 by EDAP TMS, the US healthcare insurance firm CIGNA has agreed to cover the use of high-intensity focal ultrasound (HIFU) as a second-line, salvage therapy for men with radiorecurrent prostate cancer.

The misleading promotion of HIFU as a treatment for prostate cancer

We were recently made aware of a video on Facebook promoting high-intensity focused ultrasound (HIFU) as a treatment for prostate cancer. The video promotes the services of a particular group of physicians who specialize in this form of treatment. They are, of course, entirely entitled to do this.

Salvage HIFU as a treatment for radiorecurrent localized prostate cancer

Although there has been some exploratory work in this area, the available data on the outcomes of patients treated with high-intensity focused ultrasound (HIFU) as a form of salvage therapy for men with biochemical recurrence after first-line radiation therapy are extremely limited.

Practical aspects of deciding whether HIFU is an appropriate treatment “for you”

An article by Julie Appleby of Kaiser Health News, posted yesterday on the STAT health news web site, asks whether high-intensity focused ultrasound (HIFU) is being “over-sold” to prostate cancer patients based on the limited outcome data currently available.

Salvage HIFU in men with a rising PSA after first-line surgery

We have long presumed that it would be possible to consider high-intensity focused ultrasound (HIFU) as a form of salvage therapy for men with biochemically recurrent disease after either surgery or radiation therapy. Now there are some data on this concept.

Yet another new type of HIFU is now in Phase II clinical trials

Another breathless media release has announced enrollment of the first patient into a Phase II clinical trial of yet another new form of high-intensity, focused ultrasound (HIFU) in men with low-risk and favorable, intermediate-risk, localized prostate cancer.

Let’s call this “new technology” what it is; it’s a form of HIFU

According to information in the Boston Herald earlier today, researchers at Brigham & Women’s Hospital in Boston (one of the main teaching hospitals associated with Harvard University) are testing a new form of technology to treat localized prostate cancer.

Focal HIFU in treatment of (largely) intermediate-risk prostate cancer

In addition to the French data previously referred to on this site, data from another, much larger cohort of men treated with focal, high-intensity focused ultrasound (focal HIFU) are also to be presented at the upcoming annual meeting of the American Urological Association.

HIFU for hemiablation of localized prostate cancer

A major plenary presentation at the upcoming annual meeting of the American Urological Association (AUA) will provide data from a rather small French trial of  high-intensity focused ultrasound (HIFU) in the focal management of localized prostate cancer.

5-year outcomes from a large cohort of HIFU-treated patients in the UK

For several years now, the Ahmed/Emberton-led research team in the United Kingdom (UK) has published the majority of the detailed outcomes data from treatment of men with localized prostate cancer using high-intensity focused ultrasound (HIFU). This group has now given us 5-year outcomes on a cohort of > 550 patients.

PBRT as a form of salvage radiation therapy after cryotherapy and HIFU

A new paper in “the Red Journal” prvides some information about the potential of proton beam radiation therapy (PBRT) as a salvage therapy in men who have failed either cryotherapy or first-line high-intensity focused ultrasound (HIFU) as first-line therapy for localized prostate cancer.