miR Sentinel tests 90+ percent accurate in diagnosis of prostate cancer

Earlier this year, at the annual Genitourinary Cancer symposium in San Francisco, we were first given information about the potential of three new tests for the diagnosis of prostate cancer: the so-called miR Sentinel tests from miR Scientific. … READ MORE …

BET inhibition in treatment of mCRPC

A company called Zenith Epigenetics has recently reported data from a Phase I/II clinical trial of a drug known as ZEN003604 or ZEN-3694 in the treatment of men with metastatic, castration-resistant prostate cancer (mCRPC) who have progressed on treatment with either abiraterone + prednisone or enzlautamide (Xtandi). … READ MORE …

Routine testing for COVID-19 for prostate cancer patients?

An article published in Communications Biology has suggested that all prostate cancer patients should be routinely tested fro risk of infection with COVID-19. This appears to be a questionable piece of advice for the average prostate cancer patient. … READ MORE …

Prostate cancer research: a landscape analysis

We have recently learned that Movember conducted a major landscape analysis of unmet research needs in prostate cancer that started back in 2017 and ran through 2019 but just got published in 2020. … READ MORE …

An update on AS from Dr. Peter Carroll

If you weren’t able to take part in the “live” presentation by Dr. Peter Carroll on “The past, present and future of active surveillance (AS)”, you can now view this either here on YouTube or here on the UroToday web site. This is the first in a series of four live video programs on AS-related topics. … READ MORE …

Neoadjuvant CHT + surgery for men with high-risk, localized prostate cancer

Eastham et al. have recently reported — in the Journal of Clinical Oncology — results from a randomized Phase III trial of the surgical treatment of men with high-risk forms of localized prostate cancer. … READ MORE …

PSA doubling time and prognosis for men with nmCRPC

A report this week in Urologic Oncology has confirmed the importance of PSA doubling times in understanding risk for prostate cancer progression among men with non-metastatic, castration-resistant prostate cancer (nmCRPC). … READ MORE …

COVID-19 and prostate cancer management

Do you live in the USA and believe that your prostate cancer care may have been seriously affected by the COVID-19 pandemic? … READ MORE …

Sexual function and ways to maintain it while on ADT

An upcoming article in the September issue of the journal Critical Reviews in Oncology/Hematology addresses issues related to the maintenance of sexual function for men with prostate cancer on androgen deprivation therapy (ADT). … READ MORE

Prostate cancer treatment and quality of life in the “real world”

The idea that most men will recover meaningful erectile and sexual function after treatment for prostate cancer has long been disputed by many in the patient community. We now seem to have some better data supporting the patient perspective. … READ MORE …

Webinar series on active surveillance

We have heard from Howard Wolinksy that he and others have been helping to put together a series of four webinars on different aspects of active surveillance (AS) for the management of favorable-risk prostate cancer. … READ MORE …

Do you have ADVANCED prostate cancer?

A researcher at the Medical University of South Carolina (MUSC) College of Nursing is conducting a study to better understand supportive care needs and quality of life among individuals with ADVANCED forms of prostate cancer. If you live in the USA or its territories and are a patient with ADVANCED (i.e., recurrent, non-localized, or metastatic) prostate cancer, you are potentially eligible to participate. … READ MORE …

Does “AR gain” affect responses to drugs like abiraterone in men with CRPC?

Perhaps unsurprisingly, it appears to be true that “AR gain” (see below) does indeed lower overall survival (OS) and progression-free survival (PFS) rates among men with castration-resistant prostate cancer (mCRPC). … READ MORE …

New guidelines for management of advanced prostate cancer

The American Urological Association (AUA), together with the American Society for Radiation Oncology (ASTRO) and the Society for Urologic Oncology (SUO), has just issued a new set of guidelines for the management of advanced prostate cancer (see here). … READ MORE …

The pros and cons of “screening” for prostate cancer

A newly published article by Shoag et al. in the New England Journal of Medicine (NEJM) has suggested that the risks associated with “screening” for prostate cancer using the PSA test may not be as high as previously suggested. … READ MORE …