Mutations to FOXA1 may be key to some aggressive forms of prostate cancer

A newly published study by researchers at the University of Michigan has clarified the potential roles of a transcription factor called “forkhead box A1” (FOXA1) in hormone-driven forms of prostate cancer and some other forms of hormone-driven cancer (e.g., breast cancer). … READ MORE …

Genomic data and prostate cancer risk classification: an update

Three different molecular tests have been validated as providing useful data that can help a man and his doctors to come to decisions about the management and treatment of localized prostate cancer. … READ MORE …

Decision aids and prostate cancer: how useful are they?

Your sitemaster has long had concerns about the real value of decision aids in helping men to think about and come to conclusions about controversial issues in the diagnosis and management of prostate cancer. … READ MORE …

Strategies to maintain sexual function post-treatment for prostate cancer

A research group at the University of Otago in New Zealand is continuing to investigate how men treated for prostate cancer deal with sexual dysfunction. We have helped them with this before and will continue to do so. … READ MORE …

3-year outcomes of men on AS in US community urology settings

To date we have seen very few data on the long-term follow-up of men in the US being initially managed on active surveillance (AS) after diagnosis with prostate cancer out in the “real world” of community urology practice. … READ MORE …

Patient satisfaction and the management of localized prostate cancer

A recent paper from a large Swedish research group has addressed patient satisfaction and the management of localized prostate cancer — with a specific, inclusive focus on the satisfaction of men initially managed on active surveillance. … READ MORE …

FDA “fast tracks” ARV-110 for the treatment of mCRPC

At the end of May, just prior to the annual meeting of ASCO, the US Food and Drug Administration (FDA) granted fast track designation to an investigational  agent called ARV-110 for treatment of metastatic, castration-resistant prostate cancer (mCRPC). … -READ MORE …