New trial (S1802) for treatment of men with newly diagnosed, metastatic prostate cancer

Earlier this month we had mentioned hearing about a new trial to explore whether local ablation of the primary tumor could improve the outcomes of men initially diagnosed with metastatic prostate cancer. … READ MORE …

Does local treatment at time of diagnosis improve outcomes for men initially diagnosed with metastatic disease?

Over the years, a good deal of data has been accumulated suggesting that local treatment (ablation) of the primary tumor may have benefit in the long-term outcomes of men with metastatic prostate cancer at time of initial diagnosis. … READ MORE …

Targeted HIFU in the treatment of index lesions in localized prostate cancer

A new review article offers us some greater clarity related to the role of targeted, high-intensity focused ultrasound (HIFU) to treat carefully selected areas of the prostate to eliminate primary or index lesions while leaving the remainder of the prostate intact. … READ MORE …

Aggressive, neoadjuvant androgen ablation prior to surgery in higher risk prostate cancer patients

The development of drugs like abiraterone acetate and enzalutamide has stimulated new research into the use of such agents early on, in combination with first-line therapy, to see if it can affect the outcomes for men with high-risk and unfavorable intermediate-risk prostate cancer. … READ MORE …

CureTalk on focal laser ablation therapy for prostate cancer

Last Tuesday, through the CureTalks service, we held an hour-long discussion with Dr. Ara Karamanian about the evolving and potential role of focal laser ablation (FLA) in the management of prostate cancer. … READ MORE …

Another NanoKnife pilot study

We reported several months ago on a pilot study of focal irreversible electroporation (IRE or NanoKnife®) in Sydney and London. … READ MORE …

HIFU for hemiablation of localized prostate cancer

A major plenary presentation at the upcoming annual meeting of the American Urological Association (AUA) will provide data from a rather small French trial of  high-intensity focused ultrasound (HIFU) in the focal management of localized prostate cancer. … READ MORE …