Expanded access to abiraterone acetate for men with mCRPC in UK

According to a BBC News report earlier today, abiraterone acetate has been approved for use by National Health Service (NHS) patients with metastic, castration-resistant prostate cancer (mCRPC) in Northern Ireland. A decision about availability of the drug in Scotland is expected on August 13. Abiraterone is already available to NHS patients in England and in Wales.

NICE issues new and positive draft guidance on abiraterone acetate

According to information on the web site of the National Institute for Clinical Excellence (NICE), revised draft guidance has been issued by NICE regarding the routine use of abiraterone acetate. … READ MORE …

The radium-223 expanded access clinical trial

Just a quick update to information about expanded access to treatment with radium-223 — the injectable form of radiation therapy currently being developed by Bayer Healthcare and Algeta. … READ MORE …

Expanded access trial in development for radium-223 chloride (Alpharadin) in mCRPC

We have heard from one of our contacts that Bayer Healthcare (presumably in combination with their business partner, Algeta) is initiating an expanded access (compassionate use) trial of injectable radiation therapy with radium-223 chloride (Alpharadin®) for men with metastatic, castration-resistant prostate cancer (mCRPC). … READ MORE …

Production ramp-up for Provenge on track

Dendreon’s production ramp-up for sipuleucel-T (Provenge®) is on track, the company says, with manufacturing expected to be up to full speed by year’s end. All three US-based manufacturing plants will be shipping by then, and treatment with Provenge should be available at hundreds of more locations, according to a Reuters report last week. … READ MORE …

Prostate cancer and the uninsured

The costs of first-line prostate cancer treatment for uninsured men (in America as well as elsewhere) are high: anywhere from $17,000 for a course of radiation therapy upwards, depending on the center you go to and the physicians you see. … READ MORE …