Active surveillance under-used (back in 2010-2011)

A new research letter just published in JAMA Internal Medicine suggests that only about 12 percent or less of the men who are good candidates for active surveillance are actually being managed in that manner. But, … READ MORE …

Re-classification rates on repeat biopsy for men on active surveillance in the Hopkins cohort

So there is an interesting new paper on the ramifications of active surveillance in the forthcoming June issue of the Journal of Urology — based on the extensive data now collected by the Johns Hopkins group through their very conservative active surveillance cohort of > 1,200 men accumulated since 1995. … READ MORE …

Slow but increasing uptake of observation in initial management of low-risk patients

A new article by Maurice et al. in the Canadian Urological Association Journal provides detailed information about the use of initial observation as a management strategy for low-risk prostate cancer between 2004 and 2011. … READ MORE …

The risks of upgrading and progression on active surveillance

Two recent reports provide us with some further information about the possibility of progression for patients who choose active surveillance as an initial mean to manage their risk for prostate cancer. … READ MORE …

Application of active surveillance in Australia after 2008

A newly published study in BJU International has reported on the application of active surveillance in Australia (and specifically in the state of Victoria) between 2008 and 2012. … READ MORE …

Is active surveillance appropriate for men with favorable intermediate-risk prostate cancer?

In a paper in the first issue of the new journal JAMA Oncology, a group of US-based researchers argue that data from a series of > 5,000 patients treated with first-line brachytherapy suggest that men with favorable intermediate-risk prostate cancer are actually good candidates for active surveillance. … READ MORE …

When should therapeutic intervention take place for men on active surveillance?

The fact of the matter is that, as yet, we don’t have a good answer for this question, and it may be many years before we do. The reasons for this are numerous, but we are beginning to get some of the information we need to clarify the situation. … READ MORE …

HG-PIN, ASAP, and decisions about active surveillance

The presence of high-grade prostatic intraepithelial neoplasia (HG-PIN) or atypical small acinar proliferation (ASAP) in biopsy specimens does not appear to affect risk for upstaging or upgrading among men who are otherwise good candidates for active surveillance. … READ MORE …

Expert opinions on prevention, screening, and active surveillance

There are three new and useful resources now available related to the prevention of prostate cancer, screening for prostate cancer, and the role of active surveillance in the expectant management of prostate cancer. … READ MORE …

Active surveillance among African-American males — some confusion

The appropriateness and utility of active surveillance as a management strategy for African-American men diagnosed with low-risk forms of prostate cancer appears to be becoming an issue of some mild controversy. … READ MORE …

MUSIC to the ears of advocates for active surveillance

A new paper from the coordinators of the Michigan Urological Surgery Improvement Collaborative (MUSIC) suggests that as many as 50 percent of newly diagnosed patients with low-risk forms of prostate cancer in Michigan are now receiving initial management on active surveillance (AS). … READ MORE …

Baseline data from the ProtecT trial … with outcomes still to come

Many readers of this blog will be interested to look through the data on the preliminary study design and diagnostic and baseline results of the randomized, phase III ProtecT trial that have just been reported in The Lancet Oncology. … READ MORE …

Data from two large cohorts of Austalian patients on active surveillance

A new paper in BJU International reports on data from a total of 650 Australian patients managed on active surveillance for low-risk, localized prostate cancer. … READ MORE …

Urologists recommend AS more often than rad/oncs (but probably not enough)

A new article on the Medscape web site, based on an article by Kim et al. in the journal Medical Care, deals with urologists’ and radiation oncologists’ recommendations for active surveillance (AS) as an appropriate form of treatment for low-risk prostate cancer in the USA today. … READ MORE …

How to mislead the public: a case study in apparent naivety

An article in today’s Daily Telegraph in the UK starts with the misleading statement that, “Up to half of men diagnosed with prostate cancer are being given ‘false hope’ by tests that are underestimating the severity of their disease, according to the authors of a new study.” … READ MORE …