What patients think and understand can impact their decisions and their outcomes

It has long been appreciated that African-American males have higher risk for diagnosis with prostate cancer, and higher risk for prostate cancer-specific mortality, than those of other ethnic origins living in the US. … READ MORE …

Saturated fats and prostate cancer risk — again

Data from the North Carolina-Louisiana Prostate Cancer Project, a projected funded by the Department of Defense’s Prostate Cancer Research Program, have again shown that diets high in saturated fats seem to increase risk for aggressive forms of prostate cancer. … READ MORE …

Can structure of prostate acini predict for aggressiveness of prostate cancer?

A news story on the web site of St. George’s University in London, England, offers some interesting information about research into the very early stages of the development of prostate cancer — a problem about which we still know very little. … READ MORE …

SNP on chromosome 19 may be good biomarker for aggressive Gleason 7 disease

An article just published on line in Clinical Cancer Research supposedly reports the discovery of a single nucleotide polymorphism or SNP that may be useful in predicting which patients with Gleason 7 disease are most likely to have a more aggressive form of cancer. … READ MORE …

Is new oncogenic signature test really as good as the PR?

According to an article published on line in Cancer Research, a research team at the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia is claiming that they have identified an “oncogene signature” that is highly predictive for aggressive forms of prostate cancer. … READ MORE …

DNA methylation and the aggressiveness of prostate cancer

According to a media release from the Mayo Clinic earlier today, “Alterations to the ‘on-off’ switches of genes occur early in the development of prostate cancer and could be used as biomarkers to detect the disease months or even years earlier than current approaches.” … READ MORE …

Might beta-2-microglobulin be prognostic for aggessive prostate cancer?

Beta-2 -microglobulin (also known as β2-microglobulin or B2M) is a well-characterized protein that has been investigated for years because of its importance in the diagnosis and staging of patients with some types of blood cancer (lymphomas and multiple myeloma). … READ MORE …

[-2]proPSA and the detection of prostate cancer: new data

We are starting to see a increase in the publication of data about [-2]proPSA — a specific type or isoform of free PSA — and its potential relevance in the detection and diagnosis of prostate cancer. … READ MORE …

Prostate cancer news reports: Thursday, July 2, 2009

Today’s news reports discuss such issues as:

  • Sextant biopsy in diagnosis of unilateral prostate cancer
  • Aggressiveness of prostate cancer in man diagnosed with PSA < 4 ng/ml
  • The potential of 3T MRI in prostate cancer prognosis pre-surgery
  • Surgical margins and risk for biochemical recurrence post-surgery … READ MORE …

Prostate cancer aggressiveness in diabetic patients

A recently published study has suggested the possibility of an association between the aggressiveness of prostate cancer and degree of glycemic control in some patients with an existing diagnosis of diabetes. … READ MORE …

The Friday news reports (Part A): February 13, 2009

After a relatively quiet news period, the flood gates have opened again, so we shall divide today’s news reports into two postings for easier reading. We have also published a separate report on the possibility of an association between alcohol use and prostate cancer diagnosis. … READ MORE …