Why inheriting a particular gene may be important for prostate cancer patients

An important poster that your sitemaster managed to “miss” at the recent ASCO meeting (because he was at another meeting while it was being presented) has just been discussed on the MedPage Today web site. … READ MORE …

Has TOAD resolved a real and long-standing question?

So TOAD stands for “Timing of Androgen Deprivation” and refers to a randomized, multi-center, Phase III trial carried out in Australia, New Zealand, and Canada between September 3, 2004, and July 13, 2012. … READ MORE …

Adding radiation increases survival vs. lifelong hormone therapy alone in high-risk men

Long-term follow-up of a Scandinavian randomized clinical trial has confirmed the survival benefit of adding external beam radiation to permanent ADT in high-risk prostate cancer patients. … READ MORE …

Better cancer control with radiation vs. surgery in high-risk patients

Researchers at the University of Alabama at Birmingham assigned high-risk patients to receive either external beam radiation therapy with androgen deprivation therapy (RT + ADT) or to receive surgery (RP) with or without adjuvant/salvage radiation. … READ MORE …

ADT and the risk for depression

It will come as no great surprise to most readers of this blog that androgen deprivation therapy (ADT) used in the treatment of  men with progressive forms of prostate cancer comes with a significant risk for depression (as well as other effects on cognitive function). … READ MORE …

ADT + bevacizumab as first-line treatment of recurrent prostate cancer

Data from a small, randomized, Phase II, clinical trial have suggested a possible role for bevacizumab (Avastin) in the treatment of men with recurrent prostate cancer along with androgen deprivation therapy (ADT). … READ MORE …

ROR-γ: a new way to suppress androgen receptor expression?

Most of our readers will be familiar with the idea that progression of prostate cancer over time is associated with the expression of  androgen receptors (ARs) in prostate cancer tissue. … READ MORE …

Follow

Get every new post delivered to your Inbox.

Join 1,447 other followers