ADT and risk for diagnosis with dementia? “Not in the UK”, they say!

Just a few weeks ago we reported data from a study in California suggesting an association between treatment with androgen deprivation therapy (ADT) for prostate cancer and subsequent risk for diagnosis with dementia or Alzheimer’s disease. … READ MORE …

Early data from the PATCH trial in the UK

Since 2007 a randomized clinical trial in the UK (the so-called PATCH trial) has been comparing the effectiveness and safety of transdermal estradiol patches to implants of an LHRH receptor agonist (goserelin acetate) in the treatment of advanced prostate cancer. … READ MORE …

Does ADT increase risk for all types of dementia?

Back in December last year, a group of researchers suggested that androgen deprivation therapy (ADT) might be associated with increased risk for Alzheimer’s disease (see “Is ADT giving you Alheimer’s disease?“) … READ MORE …

After long-term ADT … recovery of normal hormonal function?

A group of Spanish clinical researchers have reported recent data from a small study designed to address an unanswered question about the recovery of (relatively) normal hormonal function after completion of androgen deprivation therapy (ADT). … READ MORE …

Does long-term ADT really affect cognitive function or not?

After > 50 years of use of various forms of androgen deprivation therapy (ADT), we still don’t really have a clear idea of whether or the degree to which long-term, continuous ADT can affect cognitive function — although there is no doubt at all that many patients believe it does. … READ MORE …

Is ADT giving you Alzheimer’s disease? … Another look

Late last year we reported on a study in the Journal of Clinical Oncology that suggested the possibility of a link between androgen deprivation therapy (ADT) and the onset of Alzheimer’s disease. … READ MORE …

Why inheriting a particular gene may be important for prostate cancer patients

An important poster that your sitemaster managed to “miss” at the recent ASCO meeting (because he was at another meeting while it was being presented) has just been discussed on the MedPage Today web site. … READ MORE …