AS research survey: your help still needed

As of Friday (July 22), we had received more than 250 responses to our brief survey on research into active surveillance. Most of these are from patients and some from their familial supporters (spouses, partners, etc.). However,we are still interested in getting more input — especially from clinicians, including specialists, generalists, and allied health personnel like urology nurses! … READ MORE …

Long-term use of 5-ARIs in low-risk men on AS

Perhaps unsurprisingly, your sitemaster was a little distracted on March 9 this year (by both the start of the COVID-19 chaos and by his birthday) and so he utterly missed what appears to be a rather important paper on the use of 5α-reductase inhibitors (5-ARIs) in men on active surveillance (AS) for management of low-risk forms of prostate cancer.

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Risk calculators for men already on active surveillance

The Prostate Active Surveillance Study (PASS), initially funded by the Canary Foundation, is a multi-center research study for men  with low-risk disease who have chosen active surveillance (AS) to manage their prostate cancer. Active surveillance in PASS means closely monitoring men with prostate cancer and offering treatment if test results show the cancer is getting worse. … READ MORE …

3-year outcomes of men on AS in US community urology settings

To date we have seen very few data on the long-term follow-up of men in the US being initially managed on active surveillance (AS) after diagnosis with prostate cancer out in the “real world” of community urology practice. … READ MORE …

Do men on AS need their own support groups?

Howard Wolinsky is a long-time prostate cancer patient who has been on active surveillance (AS) since his diagnosis in 2010, when one of his doctors described him as a “poster child” for active surveillance. … READ MORE …

Much more monitoring of lower risk prostate cancer in US since 2010

According to a brief research letter in the Journal of the American Medical Association this week, there was a major increase in the application of active surveillance (AS) and watchful waiting (WW) in first-line management of prostate cancer between 2010 and 2015. … READ MORE …

Is anyone with intermediate-risk prostate cancer a “good” candidate for AS?

There is no longer any doubt that men initially diagnosed with low- and very low-risk forms of prostate cancer are, in most cases, either excellent or good candidates for first-line management on active surveillance (AS). … READ MORE …

Anxiety and AS: a patient’s perspective

In his most recent commentary on living on active surveillance, journalist Howard Wolinsky writes about the issue of anxiety which can affect a significant subset of men who are appropriate candidates for active surveillance (AS) or who have difficulty staying on AS — particularly during their first two years of management using this technique. … READ MORE …

Active surveillance in management of younger men with prostate cancer

Your sitemaster has long argued that it is perfectly reasonable for many younger men diagnosed with low- and very low-risk forms of prostate cancer to be managed initially on active surveillance (despite reticence on the parts of many physicians and many patients). … READ MORE …

Active surveillance in Oz: a situation report

An interesting article published a couple of week’s ago in the Medical Journal of Australia reports on “real world issues” related to the implementation of active surveillance (AS) in Oz. … READ MORE …

The value in personalization of expectant management strategies

A recent and truly excellent review in Nature Reviews: Urology offers us a very thoughtful set of insights on the role of “expectant” and “conservative” management (i.e., active surveillance and watchful waiting) in the care of men with prostate cancer today. … READ MORE …

MUSIC to the ears of advocates for active surveillance

A new paper from the coordinators of the Michigan Urological Surgery Improvement Collaborative (MUSIC) suggests that as many as 50 percent of newly diagnosed patients with low-risk forms of prostate cancer in Michigan are now receiving initial management on active surveillance (AS). … READ MORE …

Multidisciplinary clinics increase likelihood of acceptance of active surveillance

A newly published article in the Journal of Clinical Oncology has reported that men being seen at specialized, multidisciplinary prostate cancer clinics are nearly twice as likely to accept initial active surveillance as men consulting individual practitioners. … READ MORE …

Active surveillance — a comprehensive review (with comment)

In another article in European Urology, Dall’Era et al. have provided a thorough review of published outcome data from the seven largest known series of patients being managed under active surveillance (AS). Unfortunately the full text of this article is not available on line. … READ MORE …

Evolving “best practices” in the application of active surveillance

A new paper based on the cohort of patients being followed with active surveillance (AS) at Memorial Sloan-Kettering Cancer Center (MSKCC) has added to our understanding of the potentially optimal management of patients on AS. … READ MORE …