HG-PIN, ASAP, and decisions about active surveillance

The presence of high-grade prostatic intraepithelial neoplasia (HG-PIN) or atypical small acinar proliferation (ASAP) in biopsy specimens does not appear to affect risk for upstaging or upgrading among men who are otherwise good candidates for active surveillance. … READ MORE …

Follow-up after finding of “atypia” on initial prostate biopsy

It has long been understood that a finding of “atypia” (atypical small acinar proliferation) on an initial biopsy of the prostate is associated with an increased risk for prostate cancer, and a repeat biopsy is normally recommended for any patient with an initial finding of atypia. … READ MORE …

Prostate cancer news reports: Friday, May 29, 2009

Today’s news reports address issues such as:

  • Pro-PSA (a pecursor molecule to PSA itself)
  • A review of development-stage markers for prostate cancer detection
  • Understanding the pathology report
  • A Phase I trial of high-dose testosterone in men with metatstatic CRPC … READ MORE …

Prostate cancer news review: Thursday, July 24

Newly published studies today include data on:

  • Risk for patients with prostate atypia on biopsy having a subsequent diagnosis of prostate cancer
  • Patterns of failure of patients treated with brachytherapy for localized disease
  • Quality of life following differing types of radiotherapy
  • Second-line antiandrogen therapy following initial failure of a first-line antiandrogen in advanced prostate cancer
  • Mood and cognitive changes in men receiving intermittent androgen deprivation therapy … MORE …