Posted on March 31, 2011 by Sitemaster
It has been well understood for years that biochemical recurrence (BCR) after radical prostatectomy does not always translate into systemic progression or necessarily lead to prostate cancer metastasis and death. The “natural history” of BCR is actually very variable. … READ MORE …
Filed under: Living with Prostate Cancer, Management | Tagged: biochemical recurrence, natural history, outcome, prostatectomy, surgery | 1 Comment »
Posted on December 29, 2010 by Sitemaster
In 2009, at a presentation at the American Society for Clinical Oncology, Antonorakis et al. initially presented data, from the Johns Hopkins database, demonstrating the prognostic significance of PSA doubling time (PSADT) to long-term survival of men with progressive prostate cancer who were otherwise untreated after surgery. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: biochemical recurrence, doubling time, metastasis, mortality, prognosis, PSA, PSADT, risk, surgery, survival | 3 Comments »
Posted on November 4, 2010 by Sitemaster
A study reported this week in the Archives of Internal Medicine addresses the impact of biochemical recurrence on risk for prostate cancer-specific mortality (PCSM) among a cohort of more than 1,000 US veterans initially diagnosed and treated between 1991 and 1995. … READ MORE …
Filed under: Living with Prostate Cancer, Management | Tagged: biochemical recurrence, long-term, outcome, radical prostatectomy, radiotherapy, veteran | 7 Comments »
Posted on August 26, 2010 by Sitemaster
Biochemical failure (also known as biochemical recurrence) after first-line treatment for prostate cancer is assessed based on a rising PSA level. This is a relatively common event and can happen shortly after first line treatment or many years later. The problem is that we really don’t know how important biochemical recurrence is in an individual patient at a specific point in time. After all, if a biochemical recurrence is never going to lead to clinical symptoms of prostate cancer (let alone prostate cancer-specific mortality), why would one want to treat it? … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: biochemical recurrence, comorbidity, Management, risk, survival | Leave a comment »
Posted on March 3, 2010 by Sitemaster
A recent report in Cancer again seems to suggest that men with prostate cancer treated by radical prostatectomy (RP) who have a long time to biochemical recurrence (BCR) or a long PSA doubling time after BCR may have no higher overall risk of death than men who have no BCR at all. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: biochemical recurrence, mortality, PSA doubling time, radical prostatectomy | 1 Comment »
Posted on January 27, 2010 by Sitemaster
In today’s new reports we summarize information from recent papers dealing with:
- Apical biopsy cores in initial diagnosis of prostate cancer
- Imaging studies in the initial work-up of newly diagnosed patients
- Intrafascial dissection of peri-prostatic tissue during laparoscopic surgery
- Similarity of short-term rates of biochemical recurrence after open surgery or RALP
- Does how we define post-surgical biochemical recurrence matter — and if so, when? … READ MORE …
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: apex, biochemical recurrence, biopsy, Diagnosis, dissection, imaging, intrafascial, open, RALP, risk, robot-assisted, surgery, work-up | 1 Comment »
Posted on December 14, 2009 by Sitemaster
Researchers associated with the Duke Prostate Cancer have re-calibrated an older nomogram (used to predict the likelihood of biochemical recurrence after a radical prostatectomy or RP). The revised nomogram is now capable of predicting not only biochemical recurrence but also the much more clinically significant risk for an aggressive recurrence — in which the post-surgical PSA doubling time (PSADT) is < 9 months. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: aggressive, biochemical recurrence, PSA doubling time, PSADT, radical prostatectomy, surgery | Leave a comment »
Posted on June 11, 2009 by Sitemaster
Today’s prostate cancer news report deals with:
- A recent review of appropriate penile rehabilitation strategies
- Management of biochemical recurrence after first-line treatment failure
- Initial use of hormone therapy by French clinicians … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: biochemical recurrence, hormone therapy, penile rehabilitation, radiation therapy, surgery | Leave a comment »
Posted on April 23, 2009 by Sitemaster
We have reported separately on a study of the long-term durability of erectile function following brachytherapy using permanent seed implantation. Other reports today address:
- Literacy levels and prostate cancer communication
- Antiperspirant use as a possible cause of prostate (and breast) cancer
- A gene-based tool to predict prostate cancer risk
- Drugs in development for prostate cancer prevention
- PSA velocity and prostate cancer diagnosis
- Identification of good candidates for salvage radical prostatectomy … READ MORE …
Filed under: Diagnosis, Drugs in development, Living with Prostate Cancer, Management, Prevention, Risk, Treatment | Tagged: allele, antiperspirant, biochemical recurrence, cause, communication, Diagnosis, Literacy, Prevention, PSA velocity, risk, salvage radical prostatectomy, tool | Leave a comment »
Posted on March 23, 2009 by Sitemaster
Comment on an article on PSA velocity and prediction of biopsy outcomes has been provided separately. Today’s other news includes reports on:
- Pathological outcomes and criteria for active surveillance protocols
- Outcomes to permanent seed implant brachytherapy: age does not affect outcome
- Vacuum erectile devices and their value in post-prostatectomy erectile dysfunction
- Biochemical recurrence post-prostatectomy and the role of hormone therapy … READ MORE …
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: active surveillance, age, biochemical recurrence, brachytherapy, hormone therapy, outcomes, pathology, vacuum erectile devices, VED | Leave a comment »
Posted on February 4, 2009 by Sitemaster
It has long been known that men with apparently localized prostate cancer can relapse many years after radical prostatectomy and/or other forms of treatment that appear to have been curative. A new study from researchers at the University of Washington appears to throw some more light on why this may occur. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: biochemical recurrence, disseminated tumor cells, DTC | 11 Comments »