There is no standard definition of SECOND biochemical (PSA-detected) recurrence (BCR); that is, recurrence after both prostatectomy and salvage radiation (SRT). … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: BCR, biochemical, definition, fourth, recurrence, second, third | 2 Comments »
A media release issued yesterday by Progenics Pharmaceuticals states that the investigational imaging agent 18F-DCFPyL changed physician behavior in the management of biochemically recurrent prostate cancer in > 65 percent of patients. … READ MORE …
Filed under: Uncategorized | Tagged: 18F-DCFPyL, biochemical, change, CT, imaging, Management, PET, recurrence, scan | Leave a comment »
We didn’t expect to see data from the SPPORT trial for another 2 years, but the research team hit their recruitment goal early and have already been able to provide 5-year results. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: biochemical, clinical, post-prostatectomy, radiation, recurrence, salvage, SPPORT | 14 Comments »
Back in January this year we commented on a technique known as Retzius-sparing radical prostatectomy, which — according to its advocates — is said to facilitate recovery of erectile function post-surgery. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk | Tagged: biochemical, outcome, recurrence, Retzius-sparing, risk, surgery | Leave a comment »
In 2015, Inovio Pharmaceuticals started a Phase I trial of INO-5150 — a new type of immunotherapy using a DNA vaccine for prostate cancer which targets both prostate-specific antigen (PSA) and prostate-specific membrane antigen (PSMA). … READ MORE …
Filed under: Drugs in development, Living with Prostate Cancer, Management, Treatment | Tagged: biochemical, DNA, INO-5150, recurrence, Treatment, vaccine | Leave a comment »
Yet another genetic/genomic test (this one developed by Metamark Genetics) may have value in the assessment of risk for biochemical progression after first-line surgery for prostate cancer. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: biochemical, genomic, relapse, risk, surgery, test | 3 Comments »
There is a perception among a lot of patients — especially when they get diagnosed — that having a high Gleason score of 8, 9, or 10 is essentially a “death sentence”, regardless of how they get treated. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk | Tagged: biochemical, expectations, Gleason, high-grade, projections, recurrence, survival | 10 Comments »
We’ve looked at several retrospective studies this year that found that early ultrasensitive PSA (uPSA) results following surgery can reliably predict eventual biochemical relapse. Johns Hopkins examined its own database and found the same thing. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: biochemical, cutoff, PSA, recurrence, ultrasensitive | 5 Comments »
A new paper by a group of German researchers and clinicians has provided us with expanded insight into risk for biochemical recurrence for men with organ-confined prostate cancer and a positive surgical margin based on their post-surgical pathology report. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: biochemical, margin, positive, recurrence, risk, surgery | 1 Comment »
A new article in the February 2015 of the Journal of Urology may actually tell us as much (or more) about the difficulties of relying on data from large, retrospective analyses of single institution data as it does about the actual issue references in the headline above. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: biochemical, inhibitor, PDE5, phosphdiesterase 5, recurrence, risk, surgery | 4 Comments »
The most widely used definition of biochemical failure after primary radiation therapy is the so-called “Phoenix” definition. It’s called that because it was adopted by consensus at a meeting of the American Society for Radiation Oncology (ASTRO) in Phoenix, AZ, in 2005. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: biochemical, failure, primary, radiation therapy | 3 Comments »
In a previous article, we looked at evidence that a low detectable level of PSA predicts eventual biochemical recurrence (a confirmed PSA greater than 0.2 ng/ml) when there is aggressive pathology. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: biochemical, recurrence, risk, salvage, timing | 44 Comments »
A newly published paper by some highly regarded researchers provides data from a small, Phase II trial of Prostate Health Cocktail (PHC) — an “over-the-counter” combination herbal supplement — in the management of biochemical recurrence of prostate cancer. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: biochemical, PSA, reccurrence, rising, supplement, Treatment | 3 Comments »
It has long been understood that men with a Gleason score (GS) of 7 could be divided into two groups: those with Gleason 4 + 3 disease (in which Gleason pattern 4 was more common or “dominant”) and those with Gleason 3 + 4 disease (in which Gleason pattern 3 was dominant). … READ MORE …
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: biochemical, Gleason, pattern, progression, risk, score | 5 Comments »
THE "NEW" PROSTATE CANCER INFOLINK 