Posted on January 31, 2018 by Sitemaster
We know that “cycling” prostate cancer patients on and off high doses on testosterone while they are on androgen deprivation therapy (ADT) appears to have significant therapeutic benefit in at least some patients (see, for example, here). … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: androgen, BAT, bipolar, cycling, testosterone | 1 Comment »
Posted on January 3, 2018 by Sitemaster
Just over a year ago we wrote up a commentary on this web site entitled, “Can bipolar cycling of testosterone really cure prostate cancer?” It dealt with what is known as “bipolar androgen therapy” or BAT and referred to a Phase II clinical trial known as the RESTORE study. … READ MORE …
Filed under: Living with Prostate Cancer, Management | Tagged: androgen, BAT, bipolar, castration-resistant, enzalutamide. metastatic, mCRPC, testosterone, therapy | Leave a comment »
Posted on February 20, 2017 by Sitemaster
For those who are interested, the Answer Cancer Foundation has let us know that they will be holding an educational conference call/webinar at 8:00 pm Eastern (5:00 pm Pacific) today on the subject of bipolar androgen therapy in the treatment of advanced prostate cancer. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: androgen, BAT, bipolar, education, therapy | Leave a comment »
Posted on December 5, 2016 by Sitemaster
Some readers will already have seen headlines like this one from The Vancouver Sun and/or this one from Fox News (which originally seems to have come from The Sun in the UK). … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: advanced, androgen, BAT, bipolar, Treatment | 12 Comments »
Posted on February 4, 2016 by Sitemaster
We have seen the ability of androgen deprivation to increase the efficacy of high dose IMRT in controlling prostate cancer (see this commentary). A new study from Johns Hopkins turns conventional logic on its head … READ MORE …
Filed under: Drugs in development | Tagged: androgen, bipolar, deprivation, mice, radiation, supplementation, therapy | 1 Comment »
Posted on January 8, 2015 by Sitemaster
A report just published in Science Translational Medicine describes a new mode of treatment for men with metastatic, castration-resistant prostate cancer (mCRPC) which the authors have called “bipolar” androgen deprivation therapy (BAT). … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: androgen, bipolar, deprivation, mCRPC | 11 Comments »
Posted on July 28, 2010 by Sitemaster
Traditional forms of hormone therapy for prostate cancer are based on the idea that you reduce testosterone levels as low as you can so as to stop the ability of testosterone and its metabolites (e.g., dihydrotestosterone) to stimulate growth of prostatic tissues — including prostate cancer cells. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: androgen, bipolar, castration-resistant, CRPC, therapy | 1 Comment »