Posted on December 3, 2014 by Sitemaster
According to a research letter published in the Journal of the American Medical Association, most men in Ontario, Canada, who have androgen deprivation therapy (ADT) for treatment of prostate cancer have not been receiving bisphosphonate or comparable therapy. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: ADT, androgen, bisphosphonate, bone, deprivation | 3 Comments »
Posted on September 12, 2011 by Sitemaster
Last Friday a U.S. Food & Drug Administration (FDA) advisory committee recommended (based on a 17 to 6 vote) that the labeling of bisphosphonates needed to be updated to make it clear how long patients should take these drugs to gain the greatest benefit and suffer the least risk. … READ MORE …
Filed under: Living with Prostate Cancer, Management | Tagged: bisphosphonate, fracture, osteoporosis, Prevention, skeletal-related event | Leave a comment »
Posted on May 25, 2010 by Sitemaster
A new study has shown that the generically available, oral, bisphosphonate risedronate (Actonel) can prevent bone loss and related effects in patients receiving hormonal therapy for prostate cancer. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: bisphosphonate, bone, hormone, loss, risedronate, therapy, turnover | Leave a comment »
Posted on May 18, 2010 by Sitemaster
Men with prostate cancer who are 70 years of age or older, and who are starting adjuvant androgen deprivation therapy (ADT) for locally advanced or high-risk localized prostate cancer, should receive a bone mineral density (BMD) test followed by selective bisphosphonate therapy for those with osteoporosis, according to an article in today’s issue of Annals of Internal Medicine. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: ADT, alendronate, androgen deprivation therapy, bisphosphonate, BMD, bone mineral density, test | Leave a comment »
Posted on April 20, 2010 by Sitemaster
In today’s news reports we note new articles dealing with:
- Biopsy protocols, patient selection, and focal therapy
- Tertiary Gleason pattern 4/5 and risk for progression post-RP
- Evolving data on the uses of bisphosphonates and denosumab
- SKIs in treatment of advanced forms of prostate cancer … READ MORE …
Filed under: Diagnosis, Drugs in development, Living with Prostate Cancer, Management, Treatment | Tagged: bisphosphonate, dasatinib, denosumab, focal therapy, Gleason, saracatinib, tertiary, zoledronate | 7 Comments »
Posted on August 12, 2009 by Sitemaster
… by 23 percent, but only in combination with hormone therapy in men with metastatic disease, and in a relatively small trial. … READ MORE …
Filed under: Drugs in development, Living with Prostate Cancer, Management, Treatment | Tagged: bisphosphonate, clodronate, metastatic disease, survival | Leave a comment »
Posted on June 8, 2009 by Sitemaster
Many prostate cancer patients are advised to use bisphosphonate therapy to prevent bone loss and other bone-related adverse events associated with long-term hormonal therapy. A disorder now known as bisphosphonate-related osteonecrosis of the jaw (BRONJ) was initially associated with bisphosphonate therapy in 2003-04 and there has been extensive research on this relationship since that date. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment, Uncategorized | Tagged: bisphosphonate, jaw, osteonecrosis | 2 Comments »
Posted on January 5, 2009 by Sitemaster
There has been a lot of media noise in the past few days about two studies suggesting that a drug called alendronate (Fosamax/Merck) may be associated with a significant risk for osteonecrosis of the jaw (ONJ). … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment, Uncategorized | Tagged: alendronate, bisphosphonate, Fosamax, ONJ, osteonecrosis | Leave a comment »
Posted on September 25, 2008 by Sitemaster
According to HealthDay, a letter to the editor published today in the New England Journal of Medicine reports the very rare occurrence of inflammatory eye disease in patients being treated with bisphosphonates, e.g., alendronate (Fosamax), pamidronate (Aredia), zoledronic acid (Zometa), and others. … READ MORE …
Filed under: Uncategorized | Tagged: bisphosphonate, inflammatory eye disease | Leave a comment »