First US randomized clinical trial of oligometastasis-directed SBRT

In a recent commentary (see this link), we saw that some clinicians are making unsubstantiated claims of cancer control from treatment of oligometastases (less than 5 detected metastases). … READ MORE …

Life, behavior, and prostate cancer risk: should you be shedding a few pounds?

The capacity of the average male human to do things that are probably not very good for his health (and to not do things that probably would be good for his health) is considerable. At the most basic level, for example, most of us here in the US don’t eat very wisely and don’t take anything like enough exercise. … READ MORE …

Safety limits of SBRT dose escalation

In a recent commentary, we saw that the lack of a standard of care for stereotactic body radiation therapy (SBRT) dose escalation may put patients at risk when dose limits are pushed beyond what is customarily considered effective and safe. … READ MORE …

SBRT boost radiation therapy in intermediate- and high-risk prostate cancer

Recently we have seen evidence of improved cancer control in high-risk patients treated with external beam radiotherapy with a brachytherapy boost to the prostate. This has been demonstrated with both HDR brachytherapy boost and with LDR brachytherapy boost. … READ MORE …

Salvage SBRT for local recurrence after first-line (primary) radiation therapy

This is the second part of a two-part commentary. In the first part, we looked at studies that identified the site of failure after primary radiation treatment, … READ MORE …

Nine-year outcomes after treatment with SBRT

Katz and Kang will present their 9-year outcomes on 515 patients treated by stereotactic body radiation therapy (SBRT) at the Genitourinary Cancers Symposium tomorrow … READ MORE …

SBRT for oligometastatic recurrence

Although the theory of the existence of a temporarily stable oligometastatic stage in prostate cancer is more than 20 years old, it remains unknown whether there is any benefit to pursuing curative or progression-delaying radiation (or indeed other forms of targeted treatment) if there are only a few metastases detected at recurrence. … READ MORE …