Posted on October 27, 2020 by Sitemaster
New data on this topic — from a Phase II/III clinical trial — have just been presented at the virtual annual meeting of the American Society for Radiation Oncology (ASTRO). Basically, the data from this study by Sahgal et al. indicated that 24 Gy (in two 12 Gy doses) of stereotactic body radiation therapy (SBRT) was more effective in the elimination of spinal pain in patients with metastatic cancer as compared to 20 Gy (in five 4 Gy doses) of conventional, external beam radiation therapy (EBRT).
… READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: bone, EBRT, metastatic, pain, radiation, SBRT, spine | 3 Comments »
Posted on August 31, 2019 by Sitemaster
The second day of the APCCC here in Basel ran for 10 hours and encompassed a total of six sessions, as follows: … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Treatment | Tagged: advanced, APCCC, bone, castration-resistant, castration-sensitive, future, metastatic, side effects | Leave a comment »
Posted on August 2, 2019 by Sitemaster
In 2011, the American Society for Radiation Oncology (ASTRO) issued a consensus statement as part of its “Choosing Wisely” campaign that found that 30 Gy in 10 fractions (treatments), 20 Gy in 5 fractions, and 8 Gy in 1 fraction all gave equivalent pain relief. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: bone, pain, radiotherapy, relief | 7 Comments »
Posted on June 16, 2017 by Sitemaster
Here in the USA, about half the patients diagnosed with low-risk prostate cancer are still (apparently) being sent for “guideline-discordant” (i.e., unnecessary) bone scans and CT scans, … READ MORE …
Filed under: Diagnosis, Management, Risk | Tagged: appropriate, bone, CT, inappropriate, scan, why | 2 Comments »
Posted on February 26, 2016 by Sitemaster
A new review article suggests the possibility that radiolabeled prostate specific membrane antigens (PSMAs) and PET scans may, at some point in the not too distant future, replace bone and CT scans in diagnosis and monitoring of men with advanced forms of prostate cancer. … READ MORE …
Filed under: Diagnosis, Drugs in development, Living with Prostate Cancer, Management | Tagged: bone, CT, gallium-68, PET, PSMA, scan | 4 Comments »
Posted on February 17, 2016 by Sitemaster
An interesting new paper in BJU International has provided us with a somewhat different perspective on which patients with prostate cancer do and do not need preventive therapy (e.g., zoledronic acid/Zometa, dasatinib/Xgeva) to minimize risk for bone fractures. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: ADT, androgen, bone, deprivation, fracture, risk | 3 Comments »
Posted on October 23, 2015 by Sitemaster
A newly published paper in the journal Cancer seems to be implying that every man with castration-resistant prostate cancer who progresses from non-metastatic to metastatic status (based on a bone scan or other indicators) should also be given a CT scan because of risk for soft tissue metastasis. … READ MORE … >
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: bone, castration-resistant, CRPC, CT, metastasis, scan | 8 Comments »
Posted on October 2, 2015 by Sitemaster
A new report in the Journal of Nuclear Medicine has suggested that it may be time to start looking seriously at whether the combined [18F]NaF/[18F]FDG PET/CT scan may be significantly better than the traditional [99m]Tc bone scan in evaluation of risk for or the actual presence of metastasis in men with prostate cancer. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk | Tagged: bone, imaging, metastasis, MRI, PET/CT, scanning, whole body | 3 Comments »
Posted on March 13, 2015 by Sitemaster
A new paper in JAMA Oncology has shown that between 2004 and 2007 nearly 45 percent of men initially diagnosed with low-risk prostate cancer were receiving unnecessary bone scans and CT scans in some regions of the USA. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk | Tagged: bone, CT, imaging, risk, scan, test | 3 Comments »
Posted on December 3, 2014 by Sitemaster
According to a research letter published in the Journal of the American Medical Association, most men in Ontario, Canada, who have androgen deprivation therapy (ADT) for treatment of prostate cancer have not been receiving bisphosphonate or comparable therapy. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: ADT, androgen, bisphosphonate, bone, deprivation | 3 Comments »
Posted on November 11, 2014 by Sitemaster
One of the problems with clinical trials for late-stage prostate cancer today is that we commonly need to follow all patients until death before we can collect sufficiently accurate data to be certain that a particular product is or is not effective in extending patient survival. … READ MORE …
Filed under: Drugs in development, Living with Prostate Cancer, Management, Treatment | Tagged: bone, BSI, endpoint, index, marker, scan, surrogate, survival | Leave a comment »
Posted on September 22, 2014 by Sitemaster
According to a newly published study in the journal Cancer Research, a collaborative research team at the Massey Cancer Center of Virgina Commonwealth University and at Johns Hopkins has developed a new, systemically administered, non-invasive, molecular-genetic technique to image bone metastases resulting from prostate cancer. … READ MORE …
Filed under: Living with Prostate Cancer, Management | Tagged: AEG-1, bone, imaging, metastasis | 3 Comments »
Posted on October 9, 2013 by Sitemaster
Data published in 2005 and later have clearly shown that — for most patients — single-fraction radiation therapy (e.g., a single dose of 8 Gy) is better than multi-fraction radiation therapy (e.g., 30 Gy given over 10 treatments) for the treatment of bone pain consequent to metastatic cancer that has spread into the bones (in prostate cancer and other forms of cancer). … READ MORE …
Filed under: Living with Prostate Cancer, Management | Tagged: bone, fraction, metastatsis, multiple, pain, palliation, radiation, single | 3 Comments »
Posted on July 25, 2013 by Sitemaster
An article published a couple of weeks ago in the Journal of the National Cancer Institute looks at the effects of a physician education campaign in Sweden to reduce the inappropriate use of bone scans and other imaging tests among men with an initial diagnosis of low-risk prostate cancer. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Risk | Tagged: bone, CT, imaging, low risk, scan | 2 Comments »
Posted on June 28, 2013 by Sitemaster
A new article from an Australian clinical research group in the journal Andrology addresses “the effectiveness of implementing standardized guidelines to mitigate metabolic and bone side effects of androgen deprivation therapy (ADT) in men with non-metastatic prostate cancer.” … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: ADT, androgen, bone, density, deprivation, metabolic syndrome, outcome | 1 Comment »
