Early data from the ASCENDE-RT trial misleadingly presented

News reports (and apparently a media release) have been suggesting that ‘A prostate cancer treatment using permanently implanted radioactive “seeds” doubles rates of 5-year tumor-free survival compared with conventional high-dose radiotherapy.’ Unfortunately, these reports are somewhat — or perhaps very — misleading. … READ MORE …

EBRT + LDRBT boost provides superior cancer control compared to EBRT alone

Numerous retrospective analyses have suggested that the combination of external beam radiation therapy (EBRT) with a low-dose-rate brachytherapy (LDRBT) boost is highly effective in controlling prostate cancer in unfavorable-risk patients. … READ MORE …

A long way from actual clinical applicability, but interesting anyway …

There was an intriguing paper in the November 2013 issue of the journal Prostate suggesting that intermittent dosing with testosterone in between doses of androgen deprivation therapies may actually help men in the early stages of castration resistance to respond better to treatment over time. … READ MORE …

Outcomes following EBRT and an SBRT “boost” for localized prostate cancer

New data from the radiotherapy group at the University of Califronia, San Francisco suggests that stereotactic body radiation (SBRT) can be used to deliver a “boost” of focused radiation after external beam radiation therapy (EBRT). High dose rate (HDR) brachytherapy has also been used in this way in the past. … READ MORE …