Prostate cancer risk calculators and the decision to have a prostate biopsy

A new paper in the Journal of Clinical Oncology provides some interesting insights into the relative merits of the two major prostate cancer risk calculators widely used today in North America: the original PCPT-based risk calculator (PRC) and the Sunnybrook risk calculator (SRC). … READ MORE …

Comparative value of two prostate cancer risk calculators in Canadian patients

A newly published study has suggested that the risk calculator based on data from the European Randomized Study of Screening for Prostate Cancer (ERSPC-RC) may be a better predictor of risk for prostate cancer in Canadians that the risk calculator based on the US-based Prostate Cancer Prevention Trial (PCPT-RC). … READ MORE …

Building familial risk into prostate cancer testing decisions

The PCPT prostate cancer risk calculator is a widely used tool designed to help men and their doctors assess whether they should have a prostate biopsy based on the patient’s age, PSA level, and supplementary data. The calculator asks about family history of prostate cancer in one simple question requiring only a Yes/No answer. … READ MORE …

A “standardized,” on-line calculator for PSADT

PSA doubling time or PSADT is a valuable prognostic factor in assessing the need for second- or even third-line treatment in men with biochemical progression of prostate cancer. … READ MORE …

The CaP Calculator: a new, sophisticated, decision-support tool

Long, long ago (in September 2008), we initially reported on the existence of a prostate cancer decision support tool (then in very early-stage development) known as the CaP Calculator. … READ MORE …

As usual … the devil is in the details

van den Bergh et al. have conducted a careful investigation of the potential problem caused by the use of different predictive tools for risk of a positive result of prostate biopsy. It is very clear that different nomograms and similar tools can produce divergent outcomes in the same man. … READ MORE …