CAR-T used in treatment of two men with mCRPC at UPenn

On a CureTalks conversation earlier today with Dr. Carl June of the University of Pennsylvania (UPenn), we learned that his team had very recently treated two men with metastatic, castration-resistant prostate cancer (mCRPC) using chimeric antibody receptor T-cell therapy (CAR-T). … READ MORE …

CAR-T in the treatment of cancer: a CureTalks telecon

On November 15, our friends at CureTalks will hold a telecon on which there will be a discussion about the current and potential future uses of CAR-T in the treatment of cancer with Prof. Carl June of the University of Pennsylvania. … READ MORE …

First clear signs that CAR-T treatment may work in advanced prostate cancer

As regular readers will be aware, we rarely comment on the earliest signals that investigational treatment X or Y might turn out to have value in the treatment of prostate cancer. There are way too many such early signals, and most of them come to naught. But there are exceptions to all general rules. … READ MORE …

FDA approves CAR T-cell therapy for treatment of acute lymphoblastic leukemia

Within the past few hours, the US Food and Drug Administration (FDA) has approved the very first form of chimeric antigen receptor (CAR) T-cell therapy for the treatment of cancer — and this is also the first true form of gene therapy to be made available here in the US. … READ MORE …

Data from the first really large trial of CAR-T in treatment of lymphoma

As yet, there has been no serious clinical exploration of whether the new types of CAR-T treatment can be applied to patients with either prostate cancer or any other form of solid tumor. … READ MORE …

More on the costs of new cancer treatments

As some of our regular readers will be aware, a new form of cancer therapy known as “chimeric antigen receptor T-cell” therapy (often known as CART or CAR-T) is currently in advanced stages of development. … READ MORE …