Mental health and ADT: an objective review

As regular readers will be aware, there has been some intense debate over the past year or so about whether there is an association between treatment with androgen deprivation therapy (ADT) and risk for dementia. … READ MORE …

“How are you feeling?” can be an important question for men on ADT

At the upcoming meeting of the American Society for Clincial Oncology (ASCO) meeting in Chicago, Dr. Alicia Morgans of Vanderbilt University will be speaking about the physical and cognitive effects of systemic therapy in older men with prostate cancer. … READ MORE …

Does long-term ADT really affect cognitive function or not?

After > 50 years of use of various forms of androgen deprivation therapy (ADT), we still don’t really have a clear idea of whether or the degree to which long-term, continuous ADT can affect cognitive function — although there is no doubt at all that many patients believe it does. … READ MORE …

A genetic reason for cognitive impairment among men on ADT?

In a paper just published on line, we finally have some sound, prospective, comparative data confirming that androgen deprivation therapy (ADT) is associated with significant risk for effects on mental cognition among men with prostate cancer when used for 6 months or longer. … READ MORE …

Cognitive therapy and living with advanced forms of prostate cancer

A group of researchers in four states in Australia have reported the initiation of a randomized clinical trial designed to reduce psychological distress and improve quality of life among men with advanced prostate cancer. … READ MORE …

ADT and cognitive function — a review and pilot study

An article just published on line in the journal Urologic Oncology looks at the vexing problem of the degree to which extended periods on androgen deprivation therapy (ADT) may have significant impact on the day-to-day cognitive functioning of at least a proportion of men with progressive forms of prostate cancer. … READ MORE …

Adverse effects of ADT in men with non-metastatic prostate cancer

Two new studies just posted on line in the Journal of Clinical Oncology specifically address some of the adverse effects associated with 12 months of continuous androgen deprivation therapy (ADT) in men with non-metastatic prostate cancer. … READ MORE …