Posted on February 25, 2021 by Sitemaster
Xofigo (radium Ra 223 dichloride) is a systemic radiopharmaceutical. Radium is chemically similar to calcium and is taken up by bones in places where bone is actively growing, as in prostate cancer bone metastases. … READ MORE …
Filed under: Drugs in development, Living with Prostate Cancer, Management, Treatment, Uncategorized | Tagged: combination, radium-223, therapy, Xofigo | Leave a comment »
Posted on February 26, 2019 by Sitemaster
We know that both abiraterone acetate (Zytiga) and enzalutamide (Xtandi) can be used to extend the survival of men with mCRPC who have already been treated with docetaxel + prednisone. However, … READ MORE …
Filed under: Uncategorized | Tagged: castration-resistant, CHEIRON, combination, docetaxel, enzalutamide, mCRPC, metastatic, trial | Leave a comment »
Posted on January 28, 2018 by Sitemaster
Many years ago, it was discovered that a moderate increase in tissue temperature can markedly improve the cancer cell killing power of ionizing radiation. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: combination, hyperthermia, practise, radiation, theory, therapy | 1 Comment »
Posted on January 7, 2017 by Sitemaster
An article published on line last year in Anticancer Research has just come to our attention. It puts forward the relatively simple proposal that by combining androgen deprivation therapy (ADT) with estrogen deprivation therapy (EDT) we might be able to significantly impact the risk for development of castration-resistant prostate cancer (CRPC). … READ MORE …
Filed under: Drugs in development, Living with Prostate Cancer, Management, Treatment | Tagged: androgen, combination, deprivation, estrogen | 17 Comments »
Posted on December 20, 2016 by Sitemaster
According to a recent media release, there was no significant benefit for the investigational combination of enzalutamide (Xtandi) + abiraterone acetate (Zytiga) + prednisone in treatment of men with chemotherapy-naive, metastatic, castration-resistant prostate cancer (cnmCRPC). … READ MORE …
Filed under: Drugs in development, Living with Prostate Cancer, Management, Treatment | Tagged: abiraterone, castration-resistant, chemotherapy-naïve, combination, CRPC, enzalutamide, metastatic | 1 Comment »
Posted on April 8, 2016 by Sitemaster
A newly published article in the journal Science Translational Medicine has questioned the merits of treating prostate cancer patients with immunotherapies while they are simultaneously being treated with medical forms of castration (androgen deprivation therapy or ADT), chemotherapy, and/or radiation therapy. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: ADT, benefit, chenotherapy, combination, immunotherapy, radiation, risk, timing | 6 Comments »
Posted on August 6, 2015 by Sitemaster
The final results of the CHAARTED trial, recommending early treatment with the combination of androgen deprivation therapy (ADT) and chemotherapy, at least in men with extensive metastasis at diagnosis, have just been published this week by Sweeney et al. in The New England Journal of Medicine (NEJM). … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Treatment | Tagged: ADT, androgen, CHAARTED, chemotherapy, combination, deprivation, Diagnosis, metastatic | 8 Comments »
Posted on April 17, 2013 by Sitemaster
There is an interesting report on the OncLive web site of a lecture by Dr. Robert Dreicer given just a few weeks ago and dealing with the sequential and combination use of new agents like abiraterone acetate, enzalutamide and others for the treatment of advanced and progressive forms of prostate cancer. … READ MORE …
Filed under: Drugs in development, Living with Prostate Cancer, Management, Treatment | Tagged: abiraterone, combination, enzalutamide, radium-223, sequencing, sipuleucel-T | 14 Comments »
Posted on January 15, 2013 by Sitemaster
It has long been an open question whether early chemotherapy might benefit selected patients with androgen-sensitive prostate cancer. However, many trials seeking to answer this question have been unable to enroll sufficient patients to provide meaningful answers to this question. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: androgen-sensistive, chemotherapy, combination, docetaxel, metastatic, outcome | 2 Comments »
Posted on February 23, 2012 by Sitemaster
A media release issued earlier today by Barvarian Nordic (the developer of Prostvac®) gives us an inkling of where we may be headed in the development of combination therapies for the management of late stage (and maybe even earlier stage) forms of prostate cancer. … READ MORE …
Filed under: Drugs in development, Living with Prostate Cancer, Management, Treatment | Tagged: castrate-resistant, combination, immunotherapeutic, ipilimumab, mCRPC, outcome, Prostvac, survival | Leave a comment »
Posted on May 7, 2011 by Sitemaster
Monique Roobol and her colleagues continue to mine data from the ERSPC and other major trials in a serious attempt to describe processes that would allow us to identify the vast majority of clinically significant prostate cancers while avoiding the unnecessary diagnosis and over-treatment of indolent disease. … READ MORE …
Filed under: Diagnosis, Risk | Tagged: biopsy, chemoprevention, combination, Diagnosis, dutasteride, risk, screening | 1 Comment »
Posted on April 29, 2010 by Sitemaster
Docetaxel + prednisone is the current standard treatment for men with castration-resistant prostate cancer (CRPC). However, the survival benefit of this form of treatment is small compared to older forms of therapy. … READ MORE …
Filed under: Drugs in development, Living with Prostate Cancer, Management, Treatment | Tagged: castration-resistant prostate cancer, combination, CRPC, docetaxel, ketoconazole | Leave a comment »
Posted on December 16, 2008 by Sitemaster
In September this year, writing from the 50th annual meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO), Dr. Eyad Abu-Isa addressed breaking news of a Scandinavian trial comparing radiotherapy + hormone therapy to radiotherapy alone in the treatment of locally advanced prostate cancer. The complete results of this study in were just published in The Lancet . … READ MORE …
Filed under: Management, Treatment | Tagged: combination, hormone therapy, radiotherapy | Leave a comment »