The other day we mentioned two articles in a recent issue of JAMA Oncology that dealt with the role of intermittent androgen deprivation therapy (IADT) in the management of progressive prostate cancer today. We have now had the good fortune to be able to read both of the two articles in full, thanks to a kind correspondent. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: androgen, continuous, deprivation, IADT, intermittent | 6 Comments »
One of the small number of major prostate cancer presentations at the ASCO meeting this year comes from the so-called PRINCE trial of intermittent chemotherapy in men with castration-resistant prostate cancer (CRPC). … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: chemotherapy, continuous, docetaxel, intermittent, outcome | 5 Comments »
The debate over the relative values of continuous (CADT) and intermittent (IADT) forms of androgen deprivation therapy (ADT) in the treatment of advanced forms of prostate cancer has now been ongoing for years. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: ADT, androgen, CADT, continuous, deprivation, IADT, intermittent | 8 Comments »
The results of early, large, randomized trials of intermittent (IADT) vs. continuous androgen deprivation therapy (CADT) have provided conflicting results. However, one of the flaws in early trials was the failure to ensure that men enrolled into these trials all actually had an optimal initial response to androgen deprivation (ADT). … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: ADT, androgen, continuous, deprivation, intermittent, outcome | 4 Comments »
We had “missed” a poster presented at the recent meeting of the European Urology Association that appears to “put to bed” — in a positive fashion — the question of a relationship between nadir serum testosterone (T) levels in men on continuous androgen deprivation therapy (ADT) and the long-term effectiveness of continuous ADT. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: ADT, androgen, continuous, deprivation, outcome, serum, T, testosterone | 1 Comment »
About 18 months ago, at the 2011 Genitourinary Cancer symposium in Orlando, Florida, Klotz et al. presented data from a large trial of intermittent (IADT) versus continuous androgen deprivation therapy (CADT) in the management of men with progressive prostate cancer after prior treatment with first- or second-line radiation therapy. We reported their data at the time. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: ADT, androgen, CADT, continuous, deprivation, IADT, intermittent, therapy | 5 Comments »
New data from the randomized FinnProstate Study VII trial comparing outcomes of men randomized to treatment with either intermittent (IAD) or continuous (CAD) androgen deprivation therapy are going to further confuse physicians and patients about the relative merits of these two types of androgen deprivation therapy. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: ADT, androgen, CAD, continuous, deprivation, IAD, intermittent | 7 Comments »
Today at the ASCO annual meeting, Maha Hussein presented the results a long-term, international, randomized trial of intermittent androgen deprivation (IAD) versus continuous androgen deprivation (CAD) in men with hormone-sensitive, metastatic prostate cancer. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: androgen deprivation, continuous, hormone therapy, intermittent, outcome, survival | 5 Comments »
A new article offers expert perspective on the relative merits of intermittent and continuous androgen deprivation therapy (ADT) in the treatment of men with metastatic prostate cancer or recurrence of disease following first- or second-line treatment. … READ MORE …
Filed under: Management, Treatment | Tagged: ADT, androgen deprivation, continuous, IADT, intermittent | 1 Comment »
It has been suspected for many years that intermittent androgen deprivation (ADT) might have the same or a better impact on survival of prostate cancer patients as continuous ADT, with potentially superior effects on other factors such as quality of life. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: ADT, androgen deprivation therapy, continuous, intermittent, randomized | 2 Comments »
THE "NEW" PROSTATE CANCER INFOLINK 