CTC levels as a surrogate endpoint for clinical trials in mCRPC

A newly published analysis of data from five major clinical trials involving > 6,000 patients has provided us with additional information about circulating tumor cell (CTC) levels as an endpoint for clinical trials. … READ MORE …

Of CTCs, EMT, PSA, and megakaryocytes … Huh?

A newly published study in Clinical Cancer Research has implied the potential development of a completely new and much more accurate way to be able to identify risk for metastatic prostate cancer. … READ MORE …

Is neutrophil count a marker for risk of prostate cancer mortality?

A recent article in the journal BMC Cancer has suggested a strong association between neutrophil count and risk for overall mortality among a cohort of Canadian men treated for prostate cancer with radiation therapy ± androgen deprivation therapy (ADT). … READ MORE …

Use of CTCs to assess response to abiraterone acetate at 12 weeks on therapy

Back in 2011 we reported a presentation by Scher et al. indicating that circulating tumor cell counts (CTCs) could probably be used to monitor responses to abiraterone acetate (and perhaps other forms of drug therapy) in the treatment of men with metastatic, castration-resistant prostate cancer. … READ MORE …

CTC count as a biomarker for response to chemotherapy in men with mCRPC

There is increasing evidence that circulating tumor cell (CTC) count may be important in assessing the likelihood for an optimal response to treatment with docetaxel-based chemotherapy for men with metastatic, castration-resistant prostate cancer (mCRPC). … READ MORE …

White blood cell density and risk for prostate cancer

A recent Japanese paper has suggested that a low white blood cell (neutrophil) count may be an independent predictor of risk for a positive biopsy and a diagnosis of prostate cancer. … READ MORE …