Changes to the standards for staging of prostate cancer

The most recent, 8th edition, of the American Joint Committee on Cancer (AJCC) Staging Manual has introduced some relatively minor modifications to the standards for staging of prostate cancer. … READ MORE …

Refining the criteria for selection of patients suitable for active surveillance

The question of how best to set the spectrum of criteria that indicate the suitability of an individual patient as a good candidate for active surveillance as opposed to early treatment is (as yet) not well answered. … READ MORE …

Post-surgical pathology, active surveillance, and selection of appropriate candidates for expectant management

An interesting — if unsurprising — new set of data in the Journal of Korean Medical Science has again shown that most of the current “standard” sets of criteria for selection of patients aren’t even close to being perfect at identification of “the surgically ideal” patients for management on active surveillance. … READ MORE …

What percentage of prostate cancer patients are really good candidates for active surveillance?

In addition to the new data from Johns Hopkins, reported earlier this week, that were highly supportive of active surveillance as a first-line management strategy for “favorable-risk” prostate cancer, another recent study has suggested that as many as 67 percent of newly diagnosed patients may be good candidates for such first-line management. … READ MORE …

Multiparametric MRI imaging and risk for clinically significant prostate cancer

A new paper in Urology suggests that combination of data from multiparametric magnetic resonance imaging (mpMRI) with traditional risk factors (Gleason score, clinical stage, PSA level, etc.) may be able to improve identification of men at risk for clinically significant prostate cancer at time of diagnosis. … READ MORE …

Eligibility criteria for active surveillance among men with low-risk prostate cancer

As regular readers of this blog will be aware, the urology group at Johns Hopkins in Baltimore has, for the past several years, had one of the most restrictive sets of criteria for eligibility for active surveillance as an appropriate method for the management of men initially diagnosed with low- and very low-risk prostate cancer. … READ MORE …

Klotz, Epstein criteria for active surveillance and actual surgical outcomes

There is no broad agreement agreement (yet) across the prostate cancer community about acceptable “standard” criteria for eligibility for active surveillance as a form of first-line management of low-risk prostate cancer. On the other hand, there are two well-characterized and relatively broadly applied sets of criteria: … READ MORE …