Optimal nadir PSA after salvage cryotherapy for radiorecurrent prostate cancer

According to a new article in the Journal of Endourology, the authors have identified an optimal PSA nadir level after whole-gland salvage prostate cryoablation among patients with recurrent prostate cancer. … READ MORE …

Salvage whole-gland cryoablation after failure of primary radiation therapy

After last Tuesday’s post on focal salvage therapy for management of radiorecurrent disease, we now have long-term data on the use of salvage whole-gland cryoablation in the same category of patients. … READ MORE …

PBRT as a form of salvage radiation therapy after cryotherapy and HIFU

A new paper in “the Red Journal” prvides some information about the potential of proton beam radiation therapy (PBRT) as a salvage therapy in men who have failed either cryotherapy or first-line high-intensity focused ultrasound (HIFU) as first-line therapy for localized prostate cancer. … READ MORE …

Focal cryotherapy in the treatment of localized prostate cancer

A recent article in Expert Review of Anticancer Therapy has assessed the effectiveness and safety of focal cryotherapy in the first- and second-line treatment of localized prostate cancer. … READ MORE …

Early data on targeted focal therapy in treatment of localized prostate cancer

The potential role of targeted focal therapy in the management of localized prostate cancer is yet to be well-defined, so a paper just published on line in the Journal of Urology is of value in helping us to set our expectations. … READ MORE …

Focal cryotherapy for localized prostate cancer

A new review article on the use of focal cryotherapy in the treatment of localized prostate cancer has recently been published in the journal Cancer Control. The full text of this article by Nguyen et al. is also available on the Medscape web site. … READ MORE …

Whole-gland cryotherapy vs. radical prostatectomy as first-line treatment for localized disease

Over the years there have been very few studies that have attempted to make any type of direct comparison between outcomes of patients treated with whole-gland cryotherapy and outcomes of patients treated with other standard forms of whole gland therapy for localized prostate cancer. … READ MORE …

Is salvage cryotherapy really as safe and effective as some suggest?

There have been an increasing number of articles published in the recent past suggesting salvage cryotherapy as an excellent option for the treatment of men with progressive prostate cancer after failure of first-line radiation therapy. … READ MORE …

Effectiveness and safety of two forms of salvage therapy for patients with radio-recurrent prostate cancer

Two new papers address the utility of different types of salvage therapy for men with apparently localized, recurrent prostate cancer after first-line radiation therapy: the first paper reviews available data on outcomes after salvage radical prostatectomy (SRP); the second offers data from a small, recent series of men treated with salvage cryotherapy (SCT) using third-generation cryotechnology. … READ MORE …

The management of recurrent prostate cancer after first-line therapy

Traditionally, men with prostate cancer who had recurrent disease after first-line surgery or first-line radiation therapy had a limited number of treatment options, but we are now seeing a significant expansion in the range of options available (although limited data are as yet available to support the effectiveness of nearly all these options). … READ MORE …

Focal cryotherapy: an update from the COLD registry

A new paper in BJU International offers an analysis of data on the effectiveness and safety of focal cryotherapy (partial cryoablation of the prostate) as a first-line treatment for localized prostate cancer from the national Cryo On-Line Database (COLD) registry collected between 1997 and 2007. … READ MORE …

Utilization of standard treatments for localized prostate cancer by Medicare beneficiaries

In a new paper just published on-line in the Journal of Urology, Kapoor et al. have provided data on trends in the utilization of various major types of treatment for the management of localized prostate cancer among Medicare beneficiaries in the USA between 2006 and 2008. … READ MORE …

Whole-gland cryoablation as first-line therapy in prostate cancer patients > 75 years of age

Based on data collected in the Cryo On-Line Database (COLD), Dhar et al. have just published an analysis of data from a total of 860 men, all over 75 years of age, who were treated with whole-gland cryoablation for clinically localized prostate cancer at times dating back to at least 1995. … READ MORE …

Salvage cryoablation in men with recurrent prostate cancer after first-line radiotherapy

Two recent papers from a clinical research team at the University of Western Ontario in Canada have offered us insights into the appropriate usage of cryoablation as salvage therapy for men with progressive (recurrent) prostate cancer after first-line treatment for localized and locally advanced prostate cancer. … READ MORE …

Salvage cryotherapy as second-line treatment after first-line radiation therapy

We really have no idea what the “best” way is to treat men with progressive disease after first-line radiation therapy. … READ MORE …