CT + ADT vs. 3D-CRT + ADT for first-line treatment of “high-risk” prostate cancer

A South Korean research team has just published data from a small, prospective, case-matched study comparing outcomes after cryotherapy + androgen deprivation therapy (CT + ADT) to outcomes after three-dimensional conformal radiation therapy + androgen deprivation (3D-CRT + ADT) in patients with high-risk prostate cancer. … READ MORE …

Prostate cancer news reports: Monday, July 26, 2010

There are several interesting new publications worth commenting on this morning — all in the evolving research field as opposed to current clinical practice:

  • Angiogenic effect of a specific statin on prostate cancer development
  • Synergistic impact of calcitriol on cryotherapy
  • Hybrid imaging techniques and prostate cancer
  • GTI-2040 in treatment of CRPC … READ MORE …

10-year follow-up data on cryotherapy for prostate cancer

In a newly published report, a team of clinicians from Columbia University Medical Center has provided data on the 10-year follow-up of a small group of patients treated with salvage or primary cryotherapy for prostate cancer. … READ MORE …

Projecting outcomes of second-line (salvage) cryotherapy

One of the problems of first-line radiation therapy is how to treat patients with a rising PSA (biochemical relapse) after it becomes clear that the rise in PSA is not simply a “biochemical bounce” in the PSA. … READ MORE …

Quality of life after first-line treatment: a prospective, comparative study

Data to be published in the May 2010 issue of the Journal of Urology are going to make a lot of urologists rather less than happy about the implications for the use of radical prostatectomy as first-line treatment for prostate cancer. … READ MORE …

Prostate cancer news reports: Monday, March 29, 2010

News reports over the weekend included:

  • Various review articles dealing with such matters as Gleason grading, numbers of cores taken at biopsy, the need for lymph node dissection, surgical technique and surgical margin control, and cryotherapy
  • The effect of a water extract of white cocoa tea on prostate cancer cells in vitro and in a mouse model … READ MORE …

QOL after cryotherapy vs. EBRT

Earlier this year we reported the initial results of a truly randomized Canadian trial of cryotherapy vs. external beam radiation therapy (EBRT) for the treatment of localized prostate cancer. The same group of authors have now reported follow-up data on quality of life. … READ MORE …

5-year biochemical recurrence rates after first-line cryotherapy

A recent publication has correlated nadir post-cryoablation PSA levels (i.e., the lowest PSA level achieved by the patient after treatment) with long-term biochemical disease-free survival in a risk-stratified cohort of patients with prostate cancer treated with cryoablation. … READ MORE …

Prostate cancer news reports: Wednesday, July 8, 2009

Today’s prostate cancer news reports cover items on:

  • Assessment of quality of life after radical prostatectomy
  • Permanent seed brachytherapy in treatment of localized disease
  • Cryotherapy in treatment of patients with Gleason 8-10 localized disease
  • Actonel and/or estradiol in prevention of SREs … READ MORE …

Prostate cancer news reports: Wednesday, June 24, 2009

Today’s news reports include discussion of items on:

  • Prostate cancer risk awareness
  • Improving cryotherapy technique with 3D ultrasound
  • Interposition (“sural”) nerve grafting
  • Post-brachytherapy “PSA bounce”
  • The potential of targeted, peptide-linked, α-emitting radioisotopes … READ MORE …

Cryotherapy for localized prostate cancer today: a cryotherapist’s opinion

Dr. Aaron Katz has been practicing cryotherapy at Columbia University Medical Center in New York since 1993, so one could reasonably expect him to have a sophisticated appreciation for the pros and cons of this technique. … READ MORE …

More weekend news reports: April 19, 2009

The reports discussed below deal with:

  • Positron emission tomography in prostate cancer management
  • HIFU and cryotherapy in focal therapy for prostate cancer
  • Does a prior TURP affect outcomes to radical prostatectomy? … READ MORE …

The Tuesday news update: March 10, 2009

Today’s news reports include items on:

  • Risk for prostate cancer
  • Patient decisions about sexual functionality and prostate cancer treatment
  • Whole gland and focal cryotherapy
  • Testosterone replacement after prostate cancer therapy

and other items. … READ MORE …

More from the GU Oncology symposium — Part 1

We aren’t even going to try to report on all of the presentations and abstracts for this meeting. For people who want to look through this material for themselves, the majority of the prostate cancer abstracts for papers presented yesterday and today are already available on line on the ASCO web site. What we want to do is call out some very specific papers that demonstrated particularly interesting results. … READ MORE …

“New” treatments for localized prostate cancer: an expert overview

A small international group of very highly respected experts has just published an important review of the current evidence surrounding the application of a  number of the new and/or evolving treatments available for management of localized prostate cancer, with an emphasis on the potential of focal therapy. … READ MORE …