Some 15 months ago, we reported the initial, primary results of the TOAD trial, which showed an overall survival benefit for immediate as opposed to delayed initiation of androgen deprivation therapy (ADT) in non-metastatic patients considered to be inappropriate for curative therapy. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: ADT, androgen, delayed, deprivation, immediate, quality of life, survival, TOAD | 6 Comments »
So TOAD stands for “Timing of Androgen Deprivation” and refers to a randomized, multi-center, Phase III trial carried out in Australia, New Zealand, and Canada between September 3, 2004, and July 13, 2012. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: ADT, androgen, delayed, deprivation, immediate, randomized, trial | 3 Comments »
In another paper just published on-line in JAMA Internal Medicine this week, the authors have provided additional data indicating — once again — the lack of any value of primary androgen deprivation therapy (ADT) in the management of early-stage, localized prostate cancer among older patients. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Treatment | Tagged: ADT, androgen, delayed, deprivation, early, hormone, primary, therapy | Leave a comment »
A fascinating new paper based on data from the Prostate Cancer DataBase Sweden provides important insight into the consequences of delayed diagnosis and potential under-treatment of men who are diagnosed with locally advanced prostate cancer. … READ MORE …
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: delayed, Diagnosis, locally advanced, mortality, prostate cancer-specific | 14 Comments »
One of the major debates about the appropriate management of prostate cancer is whether deferral of treatment by low-risk patients is or is not associated with an increase in risk for disease progression and prostate cancer-specific mortality post-treatment. … READ MORE …
Filed under: Diagnosis, Management, Risk, Treatment, Uncategorized | Tagged: deferred, delayed, outcome, surgery | 3 Comments »
In March this year we reported briefly on an article by Van Poppel et al. reviewing available data on the adjuvant and the delayed use of hormone therapy in the treatment of prostate cancer and the related issue of PSA recurrence (particularly in high risk patients). … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: adjuvant, ADT, androgen deprivation therapy, delayed, immediate | Leave a comment »
The most important piece of news today is the publication of the final result of the EORTC 30846 study comparing early and delayed hormone therapy. Other news includes:
Filed under: Diagnosis, Living with Prostate Cancer, Management, Treatment | Tagged: delayed, fat, immediate, PSA, risk, surgery, Treatment, vaccine | 2 Comments »
THE "NEW" PROSTATE CANCER INFOLINK 