PSA density vs. PSA level and the prediction of prostate cancer risk

A newly published study in the journal Urology (the “Gold Journal”) has suggested that — at least for patients with a PSA level between 4 and 10 ng/ml — PSA density may be better than PSA level in the determination of which of these patients need to go on to have a biopsy. … READ MORE …

Do African Americans with low-risk prostate cancer have lower PSA density than comparable Caucasians?

There have been a number of suggestions (as yet unproven) that African American men (and perhaps other men of black African ethnicity) may be less good candidates for active surveillance than men of Caucasian and Hispanic ethnicity. … READ MORE …

PCA3 density as a marker for prostate cancer risk?

Regular readers will be aware that a PSA density (i.e., PSA ÷ prostate volume) > 0.15 has been identified and characterized as a risk factor for clinically significant prostate cancer by researchers at Johns Hopkins. … READ MORE …

Criteria for active surveillance are gradually improving

Being diagnosed with low-risk prostate cancer is a good reason to consider management under active surveillance (as opposed to immediate, early intervention) … but active surveillance won’t be right for every low-risk patient! … READ MORE …

Prevention of bone-related and metabolic complications of treatment for men on ADT

A new article from an Australian clinical research group in the journal Andrology addresses “the effectiveness of implementing standardized guidelines to mitigate metabolic and bone side effects of androgen deprivation therapy (ADT) in men with non-metastatic prostate cancer.” … READ MORE …

ADT, bone architecture, and “virtual bone biopsies”

A recent study reported in the Journal of Clinical Endocrinology and Metabolism has been receiving a good deal of media attention, although its immediate clinical importance wouldn’t appear to be particularly high. … READ MORE …

AUA report and update no. 6: Monday, April 27, 2009

We learned a few other interesting tidbits during a variety of sessions and conversations today. … READ MORE …