Active surveillance studies can have highly informative results — even when poorly executed!

The Göteborg group in Sweden have just published long-term follow-up data on the management of > 450 men identified with very low-, low-, and intermediate-risk prostate cancer as a consequence of the Gotebörg screening trial and managed on something they call “active surveillance” … READ MORE …

Risk category definitions, trial protocols, and clinical outcomes

Recent research data raise questions as to whether clinical trial protocols — and their results — are being skewed (notably for men with so-called “intermediate-risk” disease) by current definitions of risk category. … READ MORE …

Out from the trenches; onward to victory!

Drs Stewart and Kurzrock have just published a provocative article in the Journal of Clinical Oncology arguing that major changes are needed in the philosophic and methodologic approaches to the design and implementation of clinical trials. … READ MORE …