Mediterranean diet, active surveillance, and low-risk prostate cancer: the details

As we advised readers yesterday, a newly published study by Gregg et al. from the M. D. Anderson Cancer Center has given some clear indications that men diagnosed with lower-risk forms of prostate cancer who are initially managed on active surveillance (AS) can benefit — in terms of time to disease progression — from what is known as the Mediterranean-type diet. … READ MORE …

No measurable benefit from supplements in the VITAL trial

Two sets of results from a major trial focused on the use of supplements to prevent cancer and heart disease are published today in the New England Journal of Medicine. … READ MORE …

Is IBD a risk factor for prostate cancer — and if so, how serious?

A newly published report in European Urology has suggested that men who have inflammatory bowel disease (IBD) — either Crohn’s disease or ulcerative colitis — are at a significantly increased risk for prostate cancer over time. … READ MORE …

Liver disease as an adverse event for men on ADT

A newly published article in the Journal of Urology has indicated risk of an association between treatment with androgen deprivation therapy (ADT) and risk for a spectrum of liver disorders. … READ MORE …

Minimal residual disease and the management of prostate cancer

The concept of “minimal residual disease” or MRD and how it affects risk for cancer-specific mortality is a subject of growing importance in the management of many cancers. But it is relatively new to the world of prostate cancer. … READ MORE …

Is prostate-specific radiation still of any value in men diagnosed with distant metastases?

In some cancers, debulking of the primary tumor, also called cytoreduction, either with radiation or surgery, has been found to slow progression. Is that true of prostate cancer? … READ MORE …

Prostate cancer, cardiovascular disease, and the role of ADT

A new trial to be discussed at the Genitourinary Cancers Symposium is the RADICAL-PC trial, designed to give us a greater understanding of the roles of androgen deprivation (ADT) and other factors in causing cardiovascular disease in high-risk prostate cancer patients. … READ MORE …

Can we really re-frame low-risk prostate cancer as a chronic disease?

Many readers of this web site may be interested in a video discussion on the Medscape web site between two relatively young urologists about the implications of the Prostate Outcomes Outcomes Study (PCOS), on which we commented a few months back. … READ MORE …

Prostate cancer, Parkinson’s disease, risk, and genealogy

An article just published on line in the Archives of Neurology has suggested that there is an association between risk for Parkinson’s disease and risk for prostate cancer among families in Utah. Whether this association extends to the rest of the US population is not known at this time. … READ MORE …

Prostate cancer news reports: Wednesday, January 20, 2010

In today’s news reports we comment on three different articles dealing with radiotherapy in first-line treatment for localized prostate cancer:

  • Iodine-125-based brachytherapy without adjuvant hormone therapy or EBRT in younger males
  • Comparative outcomes of brachytherapy patients of 60 and younger and > 60 years of age
  • Radiation toxicities after EBRT in men who have had a prior TURP … READ MORE …