Examining “value” in the management of prostate cancer

Three new articles in the Journal of Oncology Practice take close look at the issue of risk/benefit and “value” in the management of prostate cancer today — and the management of advanced disease in particular. … READ MORE …

Liver disease as an adverse event for men on ADT

A newly published article in the Journal of Urology has indicated risk of an association between treatment with androgen deprivation therapy (ADT) and risk for a spectrum of liver disorders. … READ MORE …

PROs and HRQoL among patients participating in the LATITUDE trial

A newly published paper in The Lancet Oncology has provided early data from the LATITUDE trial on patient-reported outcomes (PROs) and health-related quality of life (HRQoL) for men with newly diagnosed, high-risk, metastatic, castration-naive prostate cancer. … READ MORE …

Radiation-induced fatigue and prostate cancer management

One of the annoyances associated with radiation treatments given over a long duration (for prostate cancer and for other reasons) is a growing feeling of fatigue. … READ MORE …

Mental and psychological impact of ADT on prostate cancer patients and their partners

Two recent papers have addressed evolution in our knowledge of the impact of androgen deprivation therapy (ADT) on various mental aspects of  the health of patients with prostate cancer and their partners as well. … READ MORE …

Heart-related mortality in men on ADT: a current perspective

A newly published study in BJU International suggests (unsurprisingly) that androgen deprivation therapy (ADT) is associated with an increased risk of death among men with such cardiovascular conditions as congestive heart failure or prior heart attacks. … READ MORE …

Understanding why placebos can have therapeutic benefit

Regular readers will be familiar with the fact that new drugs for prostate cancer are often tested against a “placebo.” They may also have heard the term “the placebo effect,” which generally implies that some interventions with no known (or theoretically possible) therapeutic benefit can be demonstrated to have a very real therapeutic effect. … READ MORE …