Patient choice and the effectiveness and safety of HIFU

An interesting article has just been published in the Journal of Urology which helps to provide information (and context) about the quality of data supporting the use of high-intensity focused ultrasound (HIFU) in the treatment of prostate cancer. … READ MORE …

Brachy boost therapy should be reserved for unfavorable risk patients

The ASCENDE-RT trial showed that oncological outcomes were improved among both intermediate-risk and high-risk men who were treated with external beam radiation (EBRT) and a brachytherapy boost (LDR-BT) to the prostate and adjuvant androgen deprivation therapy (ADT) (see this link). … READ MORE …

SBRT dose escalation

Is there an optimum treatment dose for sterotactic body radiation therapy (SBRT)? … READ MORE …

No need to endure 38 to 44 treatments with IMRT anymore

There have been several hypofractionation trials maturing in the last couple of years. With minor exceptions, they all tell the same story: external beam radiation therapy (EBRT) can be completed in less time without loss of efficacy or increase in toxicity. … READ MORE …

Decision making and the treatment of localized prostate cancer today

This month’s issue of Urologic Oncology contains a series of six articles that may be of particular interest to prostate cancer support group leaders and other prostate cancer educators. … READ MORE …

Effective, safe, and as fast as reasonably possible

For readers who are interested in the processes and the speed with which potential new cancer drugs can be brought to market here in the USA (and other places around the world too), there in an important article in this week’s New England Journal of Medicine. … READ MORE …

Prostate cancer screening said to be “not cost effective”

A new review article in Future Oncology has suggested that

even when based on favorable randomized controlled trials in younger age groups, prostate cancer screening is still not cost effective.

… READ MORE …

Comparative effectiveness, radiation therapy, and prostate cancer treatment

There is an interesting article about assessment of the comparative effectiveness of different types of radiation therapy in the management of prostate cancer in the December 2013 issue of Oncology. … READ MORE …

Cost-effectiveness of standard therapies for localized prostate cancer

According to a news item on the web site of the University of California, San Francisco, a new paper from a team lead by a UCSF researcher is, “The most comprehensive retrospective study ever conducted comparing how the major types of prostate cancer treatments stack up to each other in terms of saving lives and cost effectiveness.” … READ MORE …

STAMPEDE: an important trial in the management of advanced prostate cancer

Most of the time, when we talk about clinical trials of drugs (or other treatments) for prostate cancer, we are talking about trials in which new treatment X is compared to standard (current) treatment Y or, if there is no standard, new treatment Z is compared to a placebo (a benign, “dummy” substitute). … READ MORE …

Relative value of 3D-CRT, IMRT, and PBRT in prostate cancer published in JAMA

In February we reported on a presentation by Sheets et al. at the Genitourinary Cancer Symposium. The presentation addressed the comparative effectiveness and safety of  3D conformal, intensity-modulated, and proton beam forms of radiation therapy (3D-CRT, IMRT, and PBRT, respectively). … READ MORE …

Two interesting articles on Medscape recently

A couple of recent articles on the Medscape web site deal with aspects of the effectiveness and safety of robot-assisted laparoscopic prostatectomy (RALP) and various types of radiation therapy in the first-line treatment of prostate cancer. … READ MORE …

Comparative evaluation of open vs. robot-assisted surgery for localized prostate cancer

A new paper in the Scandinavian Journal of Urology and Nephrology has provided detailed information about the design and conduct of an ongoing, prospective, non-randomized trial comparing open radical retropubic prostatectomy (RRP) to robot-assisted laparoscopic radical prostatectomy (RALP) in treatment of localized prostate cancer. … READ MORE …