Avanafil in treatment of post-surgical ED for men with localized prostate cancer

Data published on line in the Journal of Urology last December suggest that the new PDE5 inhibitor known as avanafil or Stendra® is supposedly effective in combating erectile dysfunction (ED) in just over one-third of men with ED at 6 months after bilateral, nerve-sparing radical prostatectomy. … READ MORE …

Tadalafil for ED after first-line radiation therapy for prostate cancer

There are few published data on the efficacy and safety of PDE-5 inhibitors (e.g., sildenafil/Viagra and tadalafil/Cialis) in management of erectile function after the first-line treatment of prostate cancer with radiation therapy. … READ MORE …

Time-related loss of erectile function after low-dose-rate brachytherapy

It has long been understood that erectile function after first-line treatment for localized prostate cancer is affected by (a) erectile function before treatment and (b) elapsed time after treatment. However, the available data offering a careful analysis of the chronology of erectile function after first-line treatment of localized prostate cancer has been limited. … READ MORE …

Penile implants after prostate cancer treatment

A recent report from John Mulhall’s group at Memorial Sloan-Kettering Cancer Center has provided data on the use of surgical implantation of penile prostheses for management of erectile dysfunction after treatment for prostate cancer. … READ MORE …

Is ED a cause of depression in prostate cancer patients?

It is unlikely to come as any big surprise to the average prostate cancer patient who was potent before first-line therapy but has erectile dysfunction (ED) afterward that there might be an association between ED and depression after initial treatment for localized prostate cancer. … READ MORE …

Side effects of surgery among patients diagnosed in the Göteborg screening trial

In July this year, we commented on the 14-year mortality data published by Hugosson et al. from the randomized, population-based, prostate cancer screening trial initiated in Göteborg, Sweden, in 1995. … READ MORE …

Effects of prostate biopsy on voiding and erectile function

A new study from a German research group is likely to fuel concerns about some of the risks associated with prostate biopsy. … READ MORE …

Prostate cancer news reports: Tuesday, March 30, 2010

Today’s news reports address:

  • Diabetes and prostate cancer risk among Japanese men
  • The accuracy of T2w ecMRI in detection of prostate cancer
  • Escalated dose radiation therapy and treatment of localized prostate cancer
  • Erectile dysfunction and penile rehabilitation post-surgery … READ MORE …

The realities of erectile dysfunction after radical prostatectomy

We have commented previously on the increasing number of papers that appear to be looking with greater clarity at issues related to the adverse consequences of prostate cancer therapy. A new paper on the impact of “sexual bother” (for which you can read “physical or psychological distress related to sexual intercourse”) appears to be another paper in this “series.” … READ MORE …

Avanafil shows highly positive results in Phase 3 trial for ED

According to a company press release issued earlier today by VIVUS, Inc., avanafil, an investigational agent, was effective in the treatment of erectile dysfunction (ED) in some 77 percent of patients at a dose of 200 mg. … READ MORE …

ACP endorses use of PDE5 inhibitors for ED

The American College of Physicians (ACP) has just issued new guidelines that strongly endorses use of sildenafil (Viagra) and similar drugs for the treatment of erectile dysfunction (ED). … READ MORE …

Radical prostatectomy — surgeons’ web sites get a pretty poor grade!

There is extensive promotion of the various forms of radical prostatectomy as a method for the treatment of prostate cancer. However, it would be fair to say that the supposed benefits of treatment are normally given a great deal more prominence than the very real risks. … READ MORE …

ED in men screened for prostate cancer risk?

Risk for erectile dysfunction (ED) after prostate cancer treatment is commonly assumed to be a reason why many men avoid being tested for their risk for prostate cancer. Whether that is really true or not is actually not well understood. … READ MORE …

Impact of taldalafil once daily on sexual quality of life

According to a media release from Eli Lilly and Company late yesterday, a double-blind, placebo-controlled study has shown that tadalafil (Cialis) 5 mg taken once daily improved erectile function for men with erectile dysfunction (ED) and reported improvement in the sexual quality of life scores for men and their female partners. … READ MORE …

Predicting the effect of Viagra after radiation

Phosphodiesterase type 5 (PDE5) inhibitors such as sildenafil (Viagra) are now used regularly as a means to treat patients with erectile dysfunction (ED) following radiation therapy (RT) for localized prostate cancer. … READ MORE …