Early data from the PATCH trial in the UK

Since 2007 a randomized clinical trial in the UK (the so-called PATCH trial) has been comparing the effectiveness and safety of transdermal estradiol patches to implants of an LHRH receptor agonist (goserelin acetate) in the treatment of advanced prostate cancer. … READ MORE …

Older (and newer) drugs in the management of CRPC

On his Advanced Prostate Cancer blog site, Joel Nowak has just published a series of five brief articles on the opportunities offered by some older agents that are available for use as second-line therapies in the management of patients who have a rising PSA after treatment with standard forms of androgen deprivation therapy (ADT). … READ MORE …

Prostate cancer news reports: Wednesday, January 13, 2010

Today’s news reports summarize papers recently published on:

  • Optimism, pessimism, and long-term health outcomes
  • External beam radiation + hormone therapy for high-risk patients
  • Quality of life and health utility after radical prostatectomy
  • Paclitaxel + estradiol combination therapy in men progressing after docetaxel-based chemotherapy … READ MORE …

Prostate cancer news reports: Wednesday, July 8, 2009

Today’s prostate cancer news reports cover items on:

  • Assessment of quality of life after radical prostatectomy
  • Permanent seed brachytherapy in treatment of localized disease
  • Cryotherapy in treatment of patients with Gleason 8-10 localized disease
  • Actonel and/or estradiol in prevention of SREs … READ MORE …