ADT + EDT in the treatment of advanced prostate cancer?

An article published on line last year in Anticancer Research has just come to our attention. It puts forward the relatively simple proposal that by combining androgen deprivation therapy (ADT) with estrogen deprivation therapy (EDT) we might be able to significantly impact the risk for development of castration-resistant prostate cancer (CRPC). … READ MORE …

The PATCH study will continue to accrue patients in the UK

The Prostate Adenocarcinoma: TransCutaneous Hormones or PATCH trial is an ongoing study in the UK that was designed (in a series of stages) to determine whether estrogen patch therapy might be at least no worse than (i.e., “non-inferior” to) LHRH agonist therapy in suppressing androgens to castrate level. … READ MORE …

Prostate cancer news reports: Monday, October 25, 2010

Today’s news reports address:

  • Urinary estrogen metabolites and prostate cancer risk
  • Prostate hyperthermia in combination with radiation and hormone therapy
  • Stem cells and development of androgen resistance
  • Reviews of the appropriate management of high-risk, localized prostate cancer and the use of androgen deprivation therapy (ADT) … READ MORE …

Exposure to banned environmental estrogen increases risk of prostate cancer

From 1973 to 1993 the estrogenic insecticide chlordecone (marketed as Kepone) was widely used in the French West Indies to control pests in the banana crop. In the USA it was once used to bait household insect traps. … READ MORE …

Non-ASTRO prostate cancer news reports: Thursday, November 5, 2009

Other news reports today — from sources not related to the ASTRO annual meeting — address such topics as:

  • Perceptions about the US Preventive Services Task Force recommendations regarding the use of PSA testing men men > 75 years
  • Renal insufficiency in men of long-term drug therapy for prostate cancer
  • Cetuximab + doxirubicin in the treatment of CRPC
  • The mechanism of action of estrogens in treatment of advanced prostate cancer … READ MORE …

Prostate cancer news update: Friday, August 21, 2009

In today’s reports we note items related to:

  • Whether add-back estrogen improves cognitive function in men on ADT
  • Exercise and its impact on the side effects of ADT
  • A new technique for delivering prostate cancer “vaccines”
  • The potential of VEGF inhibitors in prostate cancer treatment … READ MORE …

Prostate cancer news report: Thursday, May 14, 2009

News reports today cover such issues as:

  • Vitamin D and its possible role in development of prostate cancer
  • Genetic testing among hereditary prostate cancer families
  • Sex hormone levels and cognitive function in older men … READ MORE …