Short-term ADT with RT for localized prostate cancer

The RTOG 94-08 clinical trial was designed to test the idea that just 4 months of hormone therapy, administered  before and during radiation therapy, would improved the overall survival of patients diagnosed with clinical stage T1b-T2b prostate cancer and a PSA level equal to or lower than 20 ng/ml. … READ MORE …

Chronic fatigue after first-line therapy for localized prostate cancer

There are few good data on the occurrence of chronic fatigue after first-line treatment of localized prostate cancer. … READ MORE …

Decline in sexual function after radiation therapy for prostate cancer

A newly published report suggests that sexual function does indeed decline after external beam radiation therapy (EBRT) for prostate cancer — but only over the first 2 years post-treatment. … READ MORE …

Hormones + brachytherapy + EBRT: more than we need?

A paper in press in the Journal of Urology has suggested that, for patients with intermediate-risk prostate cancer who elect treatment with a combination of standard (low dose) brachytherapy and external beam radiation therapy (EBRT), the addition of hormone therapy adds little in terms of clinical benefit. … READ MORE …

QOL after cryotherapy vs. EBRT

Earlier this year we reported the initial results of a truly randomized Canadian trial of cryotherapy vs. external beam radiation therapy (EBRT) for the treatment of localized prostate cancer. The same group of authors have now reported follow-up data on quality of life. … READ MORE …

Prostate cancer news reports: Saturday, July 18, 2009

In today’s news reports you will find items on:

  • Obesity and PSA levels
  • Outcomes after external beam radiation therapy
  • Mitoxantrone + predisone after taxotere failure … READ MORE …

Prostate cancer news reports: Friday, June 12, 2009

Todays news reports adddress:

  • Surgeon and hospital volume and outcomes to radical prostatectomy
  • Adverse events associated with the use of hypofractionated, dose-escalated, IMRT
  • Quality of sexual function after external beam radiation therapy
  • Percentage of positive biopsy cores and response to first-line hormone therapy … READ MORE …

Salvage brachytherapy after definitive EBRT

The most common method for salvage therapy in men with recurrent, localized prostate cancer after first-line external beam radiation therapy (EBRT) is surgery. However, a newly published study reports one group’s experience with salvage permanent perineal radioactive-seed implantation (SPPI) as a possible therapeutic option for recurrent prostate adenocarcinoma after EBRT. … READ MORE …

More from the GU Oncology symposium — Part 1

We aren’t even going to try to report on all of the presentations and abstracts for this meeting. For people who want to look through this material for themselves, the majority of the prostate cancer abstracts for papers presented yesterday and today are already available on line on the ASCO web site. What we want to do is call out some very specific papers that demonstrated particularly interesting results. … READ MORE …