More on familial and hereditary risk for prostate cancer

Slowly but surely we are learning more about the roles of family history and familial genetics (heredity) in determining risk for prostate cancer — and most especially risk for clinically significant forms of prostate cancer. … READ MORE …

Family history, PSA testing, and risk for diagnosis with prostate cancer

A presentation at the ongoing annual meeting of the European Association of Urology (EAU), in London, England, has reported (perhaps unsurprisingly) that PSA testing for risk of prostate cancer based on family history alone is not a very good idea. … READ MORE …

Informed patient counseling and the effect on PSA testing

We know that a family history of prostate cancer and the presence of certain genetic/genomic markers are associated with increased risk for prostate cancer in general and for some types of clinically significant prostate cancer in particular. … READ MORE …

Refining knowledge about familial risk for prostate cancer

We have known for years that if your father or your brother is diagnosed with prostate cancer, it affects your own risk for prostate cancer … but what sorts of prostate cancer are we talking about? Aggressive, indolent, metastatic, localized, what? … READ MORE …

The NCCN patient guidelines have “come of age”

Over the past weekend, we were able to review the most recent update to the National Comprehensive Cancer Network’s guidelines on treatment of prostate cancer for patients. It is our considered opinion that this booklet is now among the very best basic introductions to prostate cancer management for any newly diagnosed patient and his family. … READ MORE …

Family history and screening for prostate cancer: no evidence of benefit

In what we believe to be the first report of its kind from anywhere in the world, a new paper has reported that there seems to be no evidence that selective screening of men with a family history of prostate cancer is clinically beneficial compared to men with no family history of prostate cancer. … READ MORE …

Educating the family doctor about prostate cancer management

The August 15 issue of American Family Physician — supposedly one of the most widely read medical journals in America — carried an article by Mohan and Schellhammer entitled “Treatment options for localized prostate cancer.” Unfortunately the full text of this article is not available on line for the average reader. … READ MORE …

But does it make a blind bit of difference?

In a newly published paper in the journal Integrative Cancer Therapies, the authors report high use of vitamins and supplements among undiagnosed men with a brother who has previously been diagnosed with prostate cancer. … READ MORE …

Prostate cancer and prostate cancer-specific survival of men from breast cancer-prone families

An Australian research team has used data from 148 men from 1,423 families identified through the Kathleen Cunningham Consortium for Research into Familial Breast Cancer (kConFab) to assess the risks associated with prostate cancer in males from breast cancer-prone families, and most particularly from those families in which the BRCA2 gene mutation is prevalent. … READ MORE …

Familial risk for prostate cancer: genetics vs. disease-seeking activity

A study published yesterday in the Journal of the National Cancer Institute raises interesting questions about prostate cancer risk and family history of the disease. … READ MORE …