Phase III trial of olaparib in first-line treatment of mCRPC

Unfortunately we don’t always hear about some interesting clinical trials as early as we would like to. The following is a case in point. … READ MORE …

What’s the “best” form of first-line treatment for mHSPC today?

A new paper in the Annals of Oncology has addressed the critical question regarding what might be “the best” way we currently have to start treatment for a man newly diagnosed with metastatic, hormone-sensitive prostate cancer (mHSPC). … READ MORE …

The initial (10-year) results of the ProtecT trial: much as we might have expected?

So the majority of the readers of The “New” Prostate Cancer InfoLink will be well aware that we have never had data from a large, randomized clinical trial comparing the outcomes of the commonest first-line forms of management of men diagnosed with localized prostate cancer … READ MORE …

Alas, … the surgery vs. radiation therapy war continues …

In what certainly appears to be the largest and most thorough meta-analysis published to date, the authors conclude that surgery is a more effective first-line treatment for localized prostate cancer than radiation therapy. However, … READ MORE …

PRIAS reports data from a 5,000+ patient active surveillance study

Data from a recent paper in European Urology has further confirmed the value of active surveillance as a first-line management option for men diagnosed with low-risk prostate cancer. It has also confirm recent guidance for when men on active surveillance actually need to be advised that treatment is probably wise. … READ MORE …

Quality of life after three different first-line radiation therapies for localized disease: Part 3

This is the third and last of three reports discussing a recent, detailed paper by Evans et al. The first (Part 1) was published on Tuesday, August 25, and Part 2 on Wednesday, August 26. … READ MORE …

Quality of life after three different first-line radiation therapies for localized disease: Part 2

This is the second of three reports discussing a recent, detailed paper by Evans et al. The first (Part 1) was published yesterday, on Tuesday, August 25, and Part 3 will be published tomorrow (Thursday, August 27). … READ MORE …