So the majority of the readers of The “New” Prostate Cancer InfoLink will be well aware that we have never had data from a large, randomized clinical trial comparing the outcomes of the commonest first-line forms of management of men diagnosed with localized prostate cancer … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: first line, monitoring, outcome, ProtecT, radiation, surgery, trial | 9 Comments »
In what certainly appears to be the largest and most thorough meta-analysis published to date, the authors conclude that surgery is a more effective first-line treatment for localized prostate cancer than radiation therapy. However, … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: first line, localized, radiation, surgery, Treatment | 7 Comments »
Data from a recent paper in European Urology has further confirmed the value of active surveillance as a first-line management option for men diagnosed with low-risk prostate cancer. It has also confirm recent guidance for when men on active surveillance actually need to be advised that treatment is probably wise. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: active surveillance, first line, low risk, Management, PRIAS | 2 Comments »
This is the third and last of three reports discussing a recent, detailed paper by Evans et al. The first (Part 1) was published on Tuesday, August 25, and Part 2 on Wednesday, August 26. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: brachytherapy, first line, IMRT, quality of life, radiation, SBRT | 19 Comments »
This is the second of three reports discussing a recent, detailed paper by Evans et al. The first (Part 1) was published yesterday, on Tuesday, August 25, and Part 3 will be published tomorrow (Thursday, August 27). … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: brachytherapy, first line, IMRT, quality of life, radiation, SBRT | 1 Comment »
Some of the leading lights in radiation oncology have collaborated on a study (by Evans et al.) of patient-reported quality of life (QOL) following various primary radiation treatments for prostate cancer. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: brachytherapy, first line, IMRT, quality of life, radiation, SBRT | 1 Comment »
An excellent new review article in CA: A Cancer Journal of Clinicians, along with a research letter just published in the Journal of the American Medical Association (JAMA) have provided us with an important update on the value and the increasing acceptance of expectant management in the treatment of lower-risk forms of prostate cancer. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk | Tagged: active surveillance, expectant, first line, Management, Treatment, watchful waiting | Leave a comment »
Zumsteg et al. searched the database at Memorial Sloan-Kettering Cancer Center (MSKCC) to determine the risk factors associated with cancer progression after primary radiation treatment, and the timing of progression. They report their results in European Urology, … READ MORE …
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: failure, first line, outcome, radiation, surgery | 1 Comment »
Over the years, it has proved almost impossible to recruit patients to comparative trials of different types of first-line treatment in the management of localized prostate cancer — particularly in the USA. … READ MORE …
Filed under: Diagnosis, Management, Treatment, Uncategorized | Tagged: first line, localized, randomized, registry, SABRE1, trial | 6 Comments »
According to data to be presented at the upcoming meeting of the American Society of Clinical Oncology (ASCO), enzalutamide monotherapy substantially reduces PSA levels in androgen deprivation therapy (ADT)-naive patients with progressive or high-risk disease (including men with evident metastases). … READ MORE …
Filed under: Drugs in development, Living with Prostate Cancer, Management, Treatment | Tagged: "high risk", ADT, enzalutamide, first line, outcome, PSA | 2 Comments »
A new paper by clinical researchers in Korea has concluded that treatment with high-intensity focused ultrasound (HIFU) “does not provide effective oncologic outcomes even in low risk patients with prostate cancer as well as in the intermediate or high risk groups,” but does have a low associated incidence of treatment complications. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: complications, first line, HIFU, high-intensity focused ultrasound, outcome | 7 Comments »
An analysis of data on treatment of nearly 137,500 men treated for prostate cancer between 1991 and 2007 has suggested that permanent seed brachytherapy may be safer, less costly, and at least as effective as any other widely available form of first-line therapy for men with low- and intermediate-risk prostate cancer. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: brachytherapy, complications, cost, external beam, first line, radiation, radical prostatectomy, Treatment | 3 Comments »
The need for patients diagnosed with early stage prostate cancer to be highly involved in the decision as to which form of management they wish to be given is well understood. However, there has been a relative dearth of data on why patients actually make their individual decisions. … READ MORE …
Filed under: Diagnosis, Management, Treatment | Tagged: choice, first line, intermediate, localized, low, Management, patient, risk, Treatment | 2 Comments »
THE "NEW" PROSTATE CANCER INFOLINK 