Posted on September 16, 2014 by Sitemaster
For all of the past 30 years, it has been the accepted wisdom that starting a patient on medically induced androgen deprivation therapy (ADT, e.g., with leuproplide acetate/Lupron) during treatment of prostate cancer placed the patient at risk for an initial “flare” response that induced a short-term stimulus to serum testosterone levels and therefore to the development of any tumor. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: flare, hypothesis, reaction | 8 Comments »
Posted on June 24, 2011 by Sitemaster
A new paper in Clinical Cancer Research indicates that at least some men will have a short-term bone scan “flare” as a consequence of initiation of treatment with abiraterone acetate. The clinical significance of this flare is still to be fully evaluated. … READ MORE …
Filed under: Management, Treatment | Tagged: abiraterone, bone scan, flare | 4 Comments »
Posted on December 30, 2009 by Sitemaster
While it has never been categorically proven that adding an oral antiandrogen like flutamide or bicalutamide (Casodex) to injections of LHRH agonists (e.g., leuprolide actetate) improves overall patient survival, there had been little doubt in people’s minds that giving an antiandrogen for a week or two before a first LHRH agonist injection prevented the problem of disease “flare” associated with this first injection of the LHRH. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: antiandrogen, flare, LHRH agonist, testosterone | 1 Comment »
Posted on November 18, 2008 by Sitemaster
Today’s news items include information about:
- The potential of spinal MRI in diagnosis of men at risk for spinal metastasis
- A review of data on use of PDE5 inhibitors to manage post-surgical erectile dysfunction
- A “flare” phenomenom associated with docetaxel therapy in some patients
- The current status of the STAMPEDE clinical trial … READ MORE …
Filed under: Diagnosis, Management, Treatment | Tagged: docetaxel, flare, MRI, PDE5 inhibitors, spinal metastasis, STAMPEDE | Leave a comment »
THE "NEW" PROSTATE CANCER INFOLINK 