Focal therapy for localized prostate cancer: the “state of the art”

In a report on the UroToday web site, John Fortin, a prostate cancer patient who chose to have focal therapy himself a while ago, has reported on information presented at the 12th International Symposium on Focal Therapy and Imaging in Prostate and Kidney Cancer, which was held in Washington, DC, in February this year. … READ MORE …

“Long-term” data on FLA in the treatment of localized prostate cancer

An important new paper in the Journal of Vascular and Interventional Radiology has just provided us with the first large set of data on the outcomes of men with prostate cancer treated with focal laser ablation (FLA). … READ MORE …

How urologists are thinking about focal therapy for localized prostate cancer

A newly published study in Urologic Oncology has reported data from a survey carried out by researchers at the National Cancer Institute into “the current practice patterns and views among urologists regarding focal therapy for prostate cancer”. … READ MORE …

5-year follow-up after focal therapy with HIFU for localized prostate cancer

A new paper from the Emberton-Ahmed group in the UK has reported 5-year follow-up data from a cohort of > 600 patients with clinically significant, localized prostate cancer, all treated with focal forms of high-intensity focused ultrasound (HIFU). … READ MORE …

More reports from the EAU “Update on Prostate Cancer”

Dr. Zachary Klaassen and UroToday have provided us with four more interesting summaries of presentations by faculty at the European Association for Urology (EAU)’s meeting in Vienna last weekend. … READ MORE …

Salvage focal ablation for radio-recurrent prostate cancer

When there is a recurrence after primary radiation treatment, it is very tempting to try to identify the site(s) of local recurrence within the prostate and prostate bed and only treat those. The hope is that we can destroy any remaining cancer while keeping toxicity to the bladder, rectum, and neurovascular bundles to a minimum. … READ MORE …

A pathological “take” on the potential role of focal therapy

Various forms of focal therapy are now being used by some physicians to treat selected patients with well-identified, usually relatively small, “dominant” or “index” tumors that are confined to highly defined areas of the prostate. … READ MORE …

CureTalk on focal laser ablation therapy for prostate cancer

Last Tuesday, through the CureTalks service, we held an hour-long discussion with Dr. Ara Karamanian about the evolving and potential role of focal laser ablation (FLA) in the management of prostate cancer. … READ MORE …

Focal laser ablation — a CureTalk discussion

At 6:00 p.m. this evening, Eastern Time, here in the USA, we will be collaborating with our friends at CureTalks to provide an introduction to focal laser ablation in the treatment of prostate cancer. To sign up, to listen in, or ask questions, please click here. … READ MORE …

Yet another new type of HIFU is now in Phase II clinical trials

Another breathless media release has announced enrollment of the first patient into a Phase II clinical trial of yet another new form of high-intensity, focused ultrasound (HIFU) in men with low-risk and favorable, intermediate-risk, localized prostate cancer. … READ MORE …

Focal HIFU in treatment of (largely) intermediate-risk prostate cancer

In addition to the French data previously referred to on this site, data from another, much larger cohort of men treated with focal, high-intensity focused ultrasound (focal HIFU) are also to be presented at the upcoming annual meeting of the American Urological Association. … READ MORE …

HIFU for hemiablation of localized prostate cancer

A major plenary presentation at the upcoming annual meeting of the American Urological Association (AUA) will provide data from a rather small French trial of  high-intensity focused ultrasound (HIFU) in the focal management of localized prostate cancer. … READ MORE …

New form of focal therapy approved for treatment of low-risk prostate cancer

According to information released to the media on January 4 this year (which we have only now had brought to our attention) a combination of drug therapy with laser ablation has been approved  “for the focal treatment of early stage prostate cancer.” … READ MORE …

Focal salvage therapy for treatment of radiorecurrent prostate cancer

A new paper in the World Journal of Urology has reviewed the available evidence that focal forms of salvage therapy may be usable in men with biochemically recurrent prostate cancer after first-line radiation therapy (“radiorecurrent” prostate cancer). … READ MORE …

Data from a prospective trial of HIFU-based hemiablation for localized prostate cancer

A new report provides data from a prospective, single-center, Phase II trial of high-intensity focused ultrasound (HIFU) in prostate cancer hemiablation as a form of focal therapy. The study was carried out in Belgium. … READ MORE …