Sexual function no worse when fewer external beam radiation treatments used

The HYPRO trial was designed to detect whether hypofractionation (fewer radiation treatments) was inferior to conventional fractionation (over about 8 weeks of treatment). … READ MORE …

After long-term ADT … recovery of normal hormonal function?

A group of Spanish clinical researchers have reported recent data from a small study designed to address an unanswered question about the recovery of (relatively) normal hormonal function after completion of androgen deprivation therapy (ADT). … READ MORE …

Does long-term ADT really affect cognitive function or not?

After > 50 years of use of various forms of androgen deprivation therapy (ADT), we still don’t really have a clear idea of whether or the degree to which long-term, continuous ADT can affect cognitive function — although there is no doubt at all that many patients believe it does. … READ MORE …

ED drugs and risk for prostate cancer recurrence? … NOT!

Back in February 2015 a group of German researchers published a study suggesting that there was a small but significantly increased risk of biochemical recurrence after prostate cancer treatment among men using drugs like sildenafil (Viagra) to recover/stimulate erectile function. … READ MORE …

Well — this is a sort of progress, one hopes!

According to the abstract of a newly published paper by Krouwel et al. in Urology (“the Gold Journal”), we now have formal evidence that most urology residents in at least The Netherlands feel that they receive insufficient training in the management of men with erectile dysfunction. … READ MORE …

Expectation management and sexual/erectile outcomes after radical prostatectomy

A newly published paper in BJU International has helped to make clear that many surgical patients have unrealistic expectations about their recovery of erectile and sexual function after radical prostatectomy. … READ MORE …

Erectile function after three different types of treatment for localized prostate cancer

Another new paper has indicated that erectile function is better preserved among men treated by brachytherapy (radioactive seed implantation) than among men treated by radical prostatectomy or by external beam radiation therapy. … READ MORE …

Is ADT giving you Alzheimer’s disease?

A newly published article in the Journal of Clinical Oncology has demonstrated an association between treatment with androgen deprivation therapy (ADT) and risk for diagnosis with Alzheimer’s disease among prostate cancer patients at an average of 3 years of follow-up. However, … READ MORE …

Focal HIFU is “sexual function sparing” in a cohort of 118 selected patients

A new paper in European Urology has suggested that men with localized prostate cancer who are treated by focal forms of high-intensity focused ultrasound (HIFU) have “a return to baseline International Index of Erectile Function — erectile and total International Index of Erectile Function scores” by 6 months after treatment which was maintained at 1 year. … READ MORE …

Some refreshing truths about erectile function post-surgery

A refreshingly honest article published this year in Translational Andrology and Urology, and reprinted in full on the Medscape web site, offers a somewhat depressing assessment of the state of the art of prevention of erectile dysfunction and/or rehabilitation of erectile function in men undergoing radical prostatectomy. … READ MORE …

Erectile function post-radical prostatectomy: the past 20 years

It would not be unreasonable to think, some 30+ years after Dr. Pat Walsh started to do nerve-sparing radical prostatectomies at Johns Hopkins, that there might have been a gradual — if small — improvement in the quality of erectile and sexual function post-surgery on average over time. … READ MORE …

Can a dHACM allograft really improve sexual function post-surgery?

Our attention has been brought to a recent article suggesting that use of a “dehydrated human amnion/chorion membrane” (dHACM) allograft nerve wrap around the neurovascular bundle may help with recovery of erectile function post-surgery. … READ MORE …

Prostate biopsies and effects on erectile function post-biopsy

There have long been suggestions that having a prostate biopsy could be associated with at least a temporary decline in erectile function. A new study in BJU International has now shed more light on this matter. … READ MORE …

Erectile function prior to prostate cancer treatment: a key to expectation management

The ability to recover good erectile function after treatment for localized prostate cancer is — rather obviously — dependent on the quality of patients’ erectile function prior to any treatment. However, good data on this latter factor is not as well documented as one might like. … READ MORE …

A genetic reason for cognitive impairment among men on ADT?

In a paper just published on line, we finally have some sound, prospective, comparative data confirming that androgen deprivation therapy (ADT) is associated with significant risk for effects on mental cognition among men with prostate cancer when used for 6 months or longer. … READ MORE …