Posted on June 26, 2019 by Sitemaster
Three different molecular tests have been validated as providing useful data that can help a man and his doctors to come to decisions about the management and treatment of localized prostate cancer. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk | Tagged: Decipher, genetic, genomic, molecular, Oncotype, PROLARIS, test | 2 Comments »
Posted on April 17, 2019 by Sitemaster
In this week’s Journal of Clinical Oncology, there is a full-text article in the “Comments and Controversies” section entitled … READ MORE …
Filed under: Uncategorized | Tagged: DNA, genetic, genomic, germline, test | 2 Comments »
Posted on October 25, 2018 by Sitemaster
Many people are increasingly interested in whether genetic testing can help them to understand their risk for cancer. The basic answer is that “Yes, it can.” However, what is also clear is that it is only going to be helpful for a small percentage of the population. … READ MORE …
Filed under: Diagnosis, Risk | Tagged: genetic, genomic, germline, risk, test | 1 Comment »
Posted on April 18, 2018 by Sitemaster
One of the critical and unanswered questions about the value of genomic/genetic testing in relation to the diagnosis and prognosis of prostate cancer is, “What are the currently available tests actually telling us compared to the clinical data?” … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk | Tagged: Diagnosis, genetic, genomic, prognosis, risk, test | 2 Comments »
Posted on March 26, 2018 by Sitemaster
In an important decision announced late on Friday last week, the Centers for Medicare & Medicaid Services (CMS) announced that it had agreed to cover costs associated with genetic/genomic testing for Medicare patients with many advanced forms of cancer. … READ MORE …
Filed under: Diagnosis, Drugs in development, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: approval, coverage, genetic, genomic, next generation, NGS, sequencing, test | 1 Comment »
Posted on February 27, 2018 by Sitemaster
Over the past few years, with the increased focus on the idea of “personalized” medicine, we have become increasingly informed about and focused on correlations between genetics and genomics and risk for prostate cancer. However, … READ MORE …
Filed under: Diagnosis, Risk | Tagged: familial, genetic, grandsons, hereditary, risk, sons | 4 Comments »
Posted on February 22, 2018 by Sitemaster
Yesterday evening we were pleased to be able to collaborate with CureTalks to host a conversation with Dr. Eli Van Allen — the principal investigator for the Metastatic Prostate Cancer Project — to “spread the word” about this initiative. … READ MORE …
Filed under: Living with Prostate Cancer | Tagged: advanced, database, genetic, genomic, metastatic | Leave a comment »
Posted on February 15, 2018 by Sitemaster
On Wednesday, February 21, at 5:00 p.m. Eastern time (2:00 p.m. Pacific), we will be collaborating with CureTalks to present the next CureTalk on prostate cancer. It will address the recently launched “Metastatic Prostate Cancer Project”. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: advanced, CureTalk, database, genetic, genomic, metastatic | Leave a comment »
Posted on February 2, 2018 by Sitemaster
There’s a very nice article today on the MedPage Today web site about the medical value of “at-home genetic testing” (i.e., the sorts of tests available from companies like 23&Me and some others). … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk | Tagged: genetic, test, utility, value | 3 Comments »
Posted on January 13, 2018 by Sitemaster
Data from a new study reported in the British Medical Journal discusses a “polygenic hazard score” that can potentially be used to guide screening for aggressive prostate cancer (but only in men of European ancestry at this time). … READ MORE …
Filed under: Diagnosis, Risk | Tagged: aggressive, data, genetic, genomic, predict, risk, testing | 2 Comments »
Posted on December 20, 2017 by Sitemaster
Knowing whether you carry inherited cancer risk genes can help you to make the best decisions for your treatment and for your family. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk | Tagged: counseling, genetic, medicine, precision, testing | 1 Comment »
Posted on December 16, 2017 by Sitemaster
A newly published research letter in JAMA Oncology is entitled “Patient-paired sample congruence between 2 commercial liquid biopsy tests”. The two tests are both said — by the companies that market them — to have high clinical sensitivity and specificity in the identification of specific genetic markers associated with high-risk forms of prostate cancer. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Treatment | Tagged: biopsy, genetic, inconsistency, liquid, medicine, personalized, problem, result, test | 2 Comments »
Posted on October 17, 2017 by Sitemaster
Three articles in the October 12 issue of JAMA Oncology address the fact that a very specific germline mutation to the so-called HSD3B1 gene affects response to standard forms of initial androgen deprivation therapy and related factors. … READ MORE …
Filed under: Diagnosis, Drugs in development, Living with Prostate Cancer, Management, Risk | Tagged: 3βHSD1, ADT, genetic, germline, HSD3B1, profile, response, Treatment | Leave a comment »
Posted on July 17, 2017 by Sitemaster
A newly published paper in the journal JCO Precision Oncology confirms what many of us may have suspected — that the practical application of somatic tissue testing to clinical decision-making was low prior to 2015 . … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Treatment | Tagged: genetic, genomic, genotyping, immunohistochemistry, medicine, molecular, precision, test | 25 Comments »
Posted on June 16, 2017 by Sitemaster
A new paper in a new journal argues that all men diagnosed with advanced forms of prostate cancer should now, routinely, be undergoing tumor and germline DNA profiling … READ MORE …
Filed under: Diagnosis, Management, Risk | Tagged: analysis, genetic, genomic, targeted, testing, therapy | 2 Comments »