How many men are really benefiting from genome-targeted prostate cancer treatment?

The answer to that question, at present, is that we don’t know — but it’s probably very few indeed compared to all the men who have progressive forms of prostate cancer. … READ MORE …

Genomic testing for localized prostate cancer: an update

A relatively brief, current, full-text review article by Loeb and Ross is available on the Medscape web site and discusses the three currently available tests for assessment of genomic risk for men with localized forms of prostate cancer. … READ MORE …

Just how helpful is personalized genomic analysis anyway?

Regular readers of the medical science literature will be very conscious of the emphasis on genomic analysis of tumor specimens as a way to try to “personalize” treatment of cancers of many types — prostate cancer very specifically included. … READ MORE …

SU2C and PCF fund $10 million research study into why / how new drugs work in mCRPC

Researchers at a consortium of seven major cancer centers have been awarded a $10 million, 3-year grant to continue explorations into the individualization of treatment for men with advanced and metastatic forms of prostate cancer. The grant is funded in a collaboration between Stand Up To Cancer (SU2C) and the Prostate Cancer Foundation (PCF). … READ MORE …

Of genetics, diabetes, and prostate cancer risk

We know from a number of older, epidemiologic studies that there seems to be an inverse association between diabetes status and prostate cancer risk. In other words, people with diabetes seem to be less likely to be diagnosed with prostate cancer. … READ MORE …

Genomic risk, prostate cancer, endometrial cancer, linkage?

Under the “And this helps me how?” column we can now add the topic of a possible genetic link between endometrial cancer and prostate cancer (maybe). … READ MORE …

What if we could sequence whole prostate cancer genomes?

There has been little doubt over the years that prostate cancer was a genetically complex disease. No one has ever seriously thought that prostate cancer was the result of a single change in the DNA of the individual patient. Now we finally have some proof! … READ MORE …

Genetic markers for prostate cancer in Japanese patients

A large study of genetic markers in Japanese prostate cancer patients has clearly shown that some of the markers of prostate cancer in Caucasians do not appear in Japanese patients whereas new markers appear to be common among Japanese. … READ MORE …

Prostate cancer news reports: Saturday, June 27, 2009

Today’s news reports deal with such items as:

  • Genomic testing for prostate cancer and the value of specific SNPs
  • What do pre-treatment MRI/MRSI tests and molecular profiling add to prognostic significance?
  • Quality of life following salvage brachytherapy … READ MORE …

The news report: Friday, April 24, 2009

In today’s news report we touch on papers that address:

  • Genome studies and identification of real genomic risk for prostate cancer
  • More on the potential of 5-ARIs in prevention of prostate cancer
  • Whether we really need more studies on selenium as a potential prostate cancer prevention agent
  • The evolving potential of targeted focal therapy … READ MORE …

Some continuing biology education anyone?

The New York Times has started a series of science articles for its readers on “the frontiers of biology,” which may be helpful and entertaining for at least some readers of this blog. The first article, by Nick Wade, addresses what a genome is and how it actually works.

However, there seems to be no new article from Dana Jennings this week. We hope he’s just taking a brief break to recharge the engines.